Ophthalmol Glaucoma
Ophthalmol Glaucoma2025Journal Article

Enhanced Aqueous Humor Outflow Following Trabeculotomy in Primary Congenital Glaucoma Eyes.

IOP & Medical TherapyPediatric Glaucoma

Summary

02). Thus, AA demonstrated sustained improvement of AHO for the first time after effective IOP lowering from glaucoma surgery.

Abstract

In this study, we compared aqueous humor outflow (AHO) pathway patterns using aqueous angiography before circumferential trabeculotomy and again at subsequent follow-up, 1–2 months later, in eyes with primary congenital glaucoma (PCG; n=6). Pre-surgical and follow-up images were qualitatively and quantitatively compared. Trabeculotomy successfully lowered intraocular pressure (IOP) (28±1.3 to 11.8±2.0 mmHg; p <0.001). Qualitatively, few AHO pathways were seen at baseline that improved at follow-up. After trabeculotomy, there was an increased number of AHO branches (p=0.016) and branch junctions (p=0.02). Thus, AA demonstrated sustained improvement of AHO for the first time after effective IOP lowering from glaucoma surgery.

Keywords

AngiographyAqueous humor outflowImagingPediatric glaucomaTrabeculotomy

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Discussion

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