Online Circular Contrast Perimetry: Validity and Repeatability of Home Performance.
Yang X Chen, James Corbett, Jesse Gale, Joshua Meyerov, Angela Gong, Jason Cheng, Simon E Skalicky
Summary
OCCP retains a similar diagnostic accuracy and repeatability in home environments on personal devices compared with clinic-based environments and has the potential to be utilized as a remote tool for glaucoma screening and surveillance.
Abstract
PRECIS
Online Circular Contrast Perimetry (OCCP) offers clinically validated threshold perimetry to patients via a web application from their own devices. This study evaluates the feasibility, repeatability, and reliability of OCCP when performed in unsupervised home environments.
PURPOSE
To evaluate the feasibility, repeatability, and reliability of online circular contrast perimetry (OCCP) when performed in unsupervised home environments on personal devices.
PATIENTS AND METHODS
A total of 55 participants (20 control and 35 open angle glaucoma patients) were recruited. Participants underwent baseline visual field testing using OCCP in a clinical setting, followed by weekly unsupervised home tests over 6 weeks on their personal computers. An online survey was completed afterwards. Global perimetric indices and reliability indices were compared between clinic-based and home-based tests and analyzed to assess the repeatability and reliability of OCCP at home. Rasch analysis assessed the psychometric properties of the survey and intergroup variability.
RESULTS
No statistically significant differences were found in mean deviation (MD), pattern standard deviation (PSD), or visual index values between home and clinic tests ( P >0.05), and these values did not significantly alter over the 6 weekly at-home tests. OCCP false positive and fixation loss responses were statistically higher at home compared with baseline ( P =0.002 and P =0.001). Test-retest intraclass correlation coefficients for OCCP home use compared with in-clinic for MD ranged from 0.90 to 0.93, and for PSD ranged from 0.81 to 0.85. Bland-Altman analysis for MD revealed zero test-retest bias with limits of agreement ranging from ±5.28 to ±5.83 dB across the 6 weeks. The survey indicated high user satisfaction; however, Rasch analysis revealed suboptimal precision and targeting.
CONCLUSIONS
OCCP retains a similar diagnostic accuracy and repeatability in home environments on personal devices compared with clinic-based environments and has the potential to be utilized as a remote tool for glaucoma screening and surveillance.
Keywords
Top Research in Visual Field
Browse all →Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications.
Relationship between Optical Coherence Tomography Angiography Vessel Density and Severity of Visual Field Loss in Glaucoma.
Improving our understanding, and detection, of glaucomatous damage: An approach based upon optical coherence tomography (OCT).
In the Knowledge Library
Discussion
Comments and discussion will appear here in a future update.