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Clin Exp OphthalmolDecember 200723 citations

Rapid improvement of radiation-induced neovascular glaucoma and exudative retinal detachment after a single intravitreal ranibizumab injection.

Dunavoelgyi Roman, Zehetmayer Martin, Simader Christian, Schmidt-Erfurth Ursula


AI Summary

A case showed a single ranibizumab injection rapidly improved radiation-induced neovascular glaucoma and exudative retinal detachment from uveal melanoma, suggesting a promising, less invasive treatment option.

Abstract

Neovascular glaucoma is a serious complication arising from irradiation of uveal melanoma. Treatment options include panretinal photocoagulation, peripheral retina cryotherapy, photodynamic therapy with verteporfin, triamcinolone injections and surgical removal of the dying tumour mass. Nevertheless, enucleation of the affected eye often is inevitable. The authors describe a case report of a radiation-induced neovascular glaucoma and exudative retinal detachment caused by malignant melanoma of the uvea that was treated with intravitreal ranibizumab.


MeSH Terms

AgedAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedDrug Administration ScheduleExudates and TransudatesGlaucoma, NeovascularHumansInjectionsRadiation InjuriesRanibizumabRetinal DetachmentVitreous Body

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