Schmidt-Erfurth Ursula

Kreminger Judith E, Hollaus Marlene, Reiter Gregor S, Gumpinger Markus, Bogunovic Hrvoje, Schmidt-Erfurth Ursula et al.

High-resolution OCT showed thicker inner retinal layers after macula-off retinal detachment, and better visualized outer retinal layers than standard OCT, improving diagnostic accuracy and potentially clinical management.

Birner Klaudia, Coulibaly Leonard M, Schrittwieser Johannes, Steiner Irene, Mohamed Hamza, Schürer-Waldheim Simon et al.

This study correlated retinal layer thickness (EZ, ONL, GCL) with microperimetry sensitivity in healthy aging eyes. Key finding: thicker layers correlated with better sensitivity, providing crucial normative data for future clinical trials.

Pemp Berthold, Palkovits Stefan, Sacu Stefan, Schmidl Doreen, Garhöfer Gerhard, Schmetterer Leopold et al.

This study found that reduced retinal neurovascular response in diabetic retinopathy correlates with thinner ganglion cell layer and worse glycemic control, indicating structural and metabolic factors contribute to neurovascular dysfunction.

Eibenberger Katharina, Stifter Eva, Pusch Franz, Schmidt-Erfurth Ursula

Simultaneous bilateral pediatric cataract surgery showed comparable complication rates to unilateral or staged bilateral surgery, despite longer anesthesia, suggesting it's a safe option for children.

Gerendas Bianca S, Hatz Katja, Kaider Alexandra, Zulewski Henryk, Lehmann Roger, Montuoro Alessio et al.

This study found that well-controlled Type 1 diabetics show early retinal thickening, particularly in the ganglion cell layer, suggesting it's a potential early sign of diabetic retinopathy and swelling.

Hafner Julia, Zadrazil Markus, Grisold Anna, Ricken Gerda, Krenn Martin, Kitzmantl Daniela et al.

This study found corneal nerve loss and peripheral neuropathy worsen with advanced diabetic retinopathy, suggesting shared neurodegeneration and potential for ocular markers to reflect systemic nerve damage.

Mitsch Christoph, Holzer Stephan, Wassermann Lorenz, Resch Hemma, Urach Susanne, Kiss Barbara et al.

This study compared neuroretinal rim width measurements between Spectralis and Cirrus OCTs, finding Cirrus generally showed higher values. Clinical relevance: use the same device for glaucoma progression monitoring due to measurement differences.

Hafner Julia, Karst Sonja, Sacu Stefan, Scholda Christoph, Pablik Eleonore, Schmidt-Erfurth Ursula

This study found that in early type 2 diabetes, corneal and retinal nerve damage are independent, and only specific retinal nerve changes correlate with retinal microvascular perfusion.

Hafner Julia, Prager Sonja, Lammer Jan, Kriechbaum Katharina, Scholda Christoph, Pablik Eleonore et al.

This study found GCIPL thickness measurements from Cirrus and Spectralis OCTs differ significantly in diabetic macular edema. Clinicians must be aware these devices are not interchangeable when monitoring diabetic neurodegeneration.

Podkowinski Dominika, Philip Ana-Maria, Vogl Wolf-Dieter, Gamper Jutta, Bogunovic Hrvoje, Gerendas Bianca S et al.

This study found that neuroretinal atrophy, specifically thinning of inner retinal layers, occurs in about 11% of RVO patients after ranibizumab treatment, but did not negatively impact visual acuity.

Prager Sonja G, Lammer Jan, Mitsch Christoph, Hafner Julia, Pemp Berthold, Scholda Christoph et al.

This study found that in diabetic macular edema, reduced retinal nerve fiber layer thickness correlated with improved vision, regardless of ranibizumab or triamcinolone treatment, offering new insights into disease mechanisms.

Rezar-Dreindl Sandra, Sacu Stefan, Eibenberger Katharina, Pollreisz Andreas, Bühl Wolf, Georgopoulos Michael et al.

This study found combination therapy for persistent nAMD reduced inflammatory/angiogenic cytokines, unlike ranibizumab alone. However, both treatments yielded similar visual outcomes, suggesting cytokine modulation doesn't always translate to superior function.

Mitsch Christoph, Pemp Berthold, Kriechbaum Katharina, Bolz Matthias, Scholda Christoph, Schmidt-Erfurth Ursula

PRP for PDR causes early retinal nerve fiber layer swelling and late photoreceptor/RPE thinning, indicating diffuse inflammation and morphometric changes detectable by OCT.

Pemp Berthold, Kardon Randy H, Kircher Karl, Pernicka Elisabeth, Schmidt-Erfurth Ursula, Reitner Andreas

Averaging more OCT frames (100 vs. 1 or 16) significantly improves retinal nerve fiber layer thickness measurement reproducibility. This enhances early glaucoma detection and monitoring by reducing measurement variability.

Zotter Stefan, Pircher Michael, Götzinger Erich, Torzicky Teresa, Yoshida Hirofumi, Hirose Futoshi et al.

This study developed a new PS-OCT system, finding it accurately and reproducibly measures RNFL birefringence, retardation, and thickness, suggesting it could be a valuable tool for glaucoma diagnosis.

Serbecic Nermin, Beutelspacher Sven C, Kircher Karl, Reitner Andreas, Schmidt-Erfurth Ursula

This study found standard OCT software often misses subtle RNFL atrophy in acute optic neuritis and fellow eyes, highlighting the need for comparison with matched controls to detect silent nerve damage.

Dunavoelgyi Roman, Funk Marion, Sacu Stefan, Georgopoulos Michael, Zlabinger Gerhard, Zehetmayer Martin et al.

Uveal melanoma eyes showed significantly elevated angiogenic and inflammatory cytokines, supporting a link between inflammation and tumor growth, which could inform future therapeutic targets.

Pircher Michael, Hitzenberger Christoph K, Schmidt-Erfurth Ursula

PS-OCT provides additional tissue information by analyzing light polarization changes, offering enhanced contrast for structures like the retinal nerve fiber layer, which is clinically relevant for glaucoma and AMD diagnosis.

Serbecic Nermin, Beutelspacher Sven C, Geitzenauer Wolfgang, Kircher Karl, Lassmann Hans, Reitner Andreas et al.

This study found standard SD-OCT often misses early MS-related optic nerve damage. Comparing RNFL thickness to the fellow eye and age/sex-matched controls improves detection of subtle axonal loss.

Kriechbaum Katharina, Prager Franz, Geitzenauer Wolfgang, Benesch Thomas, Schütze Christopher, Simader Christian et al.

Anti-VEGF treatment for RVO significantly improved both retinal function and anatomy, with strong correlations between these changes, highlighting OCT's value in monitoring.

Funk Marion, Karl David, Georgopoulos Michael, Benesch Thomas, Sacu Stefan, Polak Kaija et al.

This study found neovascular AMD eyes have high VEGF and low PDGF. Ranibizumab reduced VEGF, correlating with improved vision/anatomy and disease activity, highlighting its anti-VEGF mechanism.

Funk Marion, Kriechbaum Katharina, Prager Franz, Benesch Thomas, Georgopoulos Michael, Zlabinger Gerhard J et al.

Bevacizumab for retinal vein occlusion reduced intraocular VEGF, improving vision and edema. VEGF levels correlated with disease activity, becoming measurable again when retreatment was needed.

Prager Franz, Michels Stephan, Simader Christian, Geitzenauer Wolfgang, Schmidt-Erfurth Ursula

Systemic bevacizumab for neovascular AMD improved central retinal sensitivity and reduced scotoma size, indicating functional benefits.

Dunavoelgyi Roman, Zehetmayer Martin, Simader Christian, Schmidt-Erfurth Ursula

A case showed a single ranibizumab injection rapidly improved radiation-induced neovascular glaucoma and exudative retinal detachment from uveal melanoma, suggesting a promising, less invasive treatment option.

Augustin Albert J, Schmidt-Erfurth Ursula

This study found verteporfin PDT plus intravitreal triamcinolone for occult AMD-CNV improved visual acuity over two years with fewer retreatments, suggesting enhanced outcomes compared to standard PDT.