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J GlaucomaApril 20260 citations

Outcomes of Ahmed Glaucoma Valve Implantation in the Ciliary Sulcus Versus the Anterior Chamber.

Kuroda Kohei, Hayashi Yusuke, Asaoka Satoko, Komori Tsubasa, Asada Yosuke, Iwamoto Satoshi, Hirota Akira, Sasaki Hidenori, Saeki Tadashiro, Yamagami Satoru


AI Summary

Ahmed Glaucoma Valve implantation into the ciliary sulcus offers similar eye pressure control to anterior chamber placement, with less corneal damage, despite more surgical difficulty and hyphema.

Abstract

Precis: AGV implantation through the ciliary sulcus offers similar IOP control to anterior chamber insertion with reduced corneal endothelial cell loss, despite technical difficulties during the insertion process.

Purpose

To report the surgical outcomes of Ahmed glaucoma valve (AGV) implantation through the ciliary sulcus (CS).

Patients and methods: We performed a retrospective analysis of 204 eyes of 204 patients with AGV implantation through the CS and 85 eyes of 85 patients with AGV implantation through the anterior chamber (AC). The cumulative probability of success was defined as an IOP between 5 and 18 mmHg and reduction of IOP≧20% from the preoperative IOP. Kaplan-Meier analysis evaluated success up to five years.

Results

AGV-CS/AC eyes included POAG (74/12 eyes), PACG (8/0), XFG (62/50), NVG (4/1) and secondary glaucoma (56/22), respectively. There was no significant difference in qualified success rates of AGV-CS (89.7%) and AGV-AC (87.1%). Intraoperative tube insertion difficulties occurred in 47 eyes (23.0%) in the CS group and none in the AC group. Layered hyphema was more frequently observed in CS group (25 eyes, 12.3%) than in AC group (5 eyes, 5.9%). The monthly loss of corneal endothelial cell density (per mm2) was significantly lower in CS group (14.5±20.4) than in AC group (24.5±34.3).

Conclusions

Although the higher rates of intraoperative troubles for insertion and postoperative hyphema were observed, the IOP control of AGV-CS insertion is comparable to that of AC insertion with less detrimental effects on the corneal endothelium. With appropriate techniques, CS is a reasonable insertion site for refractory glaucoma.


Key Concepts6

Ahmed Glaucoma Valve (AGV) implantation through the ciliary sulcus (CS) offers similar intraocular pressure (IOP) control to anterior chamber (AC) insertion.

Comparative EffectivenessCohortRetrospective analysisn=204 eyes (CS group), 85 eyes (AC group)Ch27Ch41

The qualified success rates for AGV-CS (89.7%) and AGV-AC (87.1%) were not significantly different, with success defined as an IOP between 5 and 18 mmHg and reduction of IOP ≥ 20% from preoperative IOP, evaluated up to five years.

Comparative EffectivenessCohortRetrospective analysisn=204 eyes (CS group), 85 eyes (AC group)Ch27Ch41

AGV implantation through the ciliary sulcus resulted in a significantly lower monthly loss of corneal endothelial cell density (14.5±20.4 per mm2) compared to anterior chamber insertion (24.5±34.3 per mm2).

Comparative EffectivenessCohortRetrospective analysisn=204 eyes (CS group), 85 eyes (AC group)Ch16Ch41

Intraoperative tube insertion difficulties occurred in 47 eyes (23.0%) in the AGV-CS group, while none occurred in the AGV-AC group.

TreatmentCohortRetrospective analysisn=204 eyes (CS group), 85 eyes (AC group)Ch41

Layered hyphema was observed more frequently in the AGV-CS group (25 eyes, 12.3%) than in the AGV-AC group (5 eyes, 5.9%).

TreatmentCohortRetrospective analysisn=204 eyes (CS group), 85 eyes (AC group)Ch24Ch41

A retrospective analysis was conducted on 204 eyes of 204 patients with AGV implantation through the ciliary sulcus and 85 eyes of 85 patients with AGV implantation through the anterior chamber.

MethodologyCohortRetrospective analysisn=204 eyes (CS group), 85 eyes (AC group)Ch27

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