Evaluation of the distribution pattern of the circumpapillary retinal nerve fibre layer from the nasal hemiretina.
Ueda Kaori, Kanamori Akiyasu, Akashi Azusa, Matsumoto Yoshiko, Yamada Yuko, Nakamura Makoto
AI Summary
Studying eyes with chiasmal damage, researchers found nasal retinal nerve fibers predominantly enter the optic disc at 1 and 5 o'clock, aiding glaucoma diagnosis by identifying specific fiber loss patterns.
Abstract
Background/aims: Chiasmal compression affects the crossed nerve fibres originating from the nasal hemiretina, as opposed to the uncrossed fibres from the temporal hemiretina. The objectives were to evaluate circumpapillary retinal nerve fibre layer (cpRNFL) thickness by spectral-domain optical coherence tomography in eyes with band atrophy (BA) accompanying temporal hemianopia due to chiasmal damage and to estimate the distribution pattern of cpRNFL from the nasal hemiretina.
Methods
This cross-sectional study included 53 eyes with optic neuropathy due to chiasmal lesions and 72 normal eyes. Visual field sensitivity (VFS) was evaluated by standard automated perimetry. Eyes with abnormalities in the nasal visual hemifield were excluded. The structure-function relationships (cpRNFL thickness and VFS in the temporal hemifield) were evaluated in eyes with BA. The base levels composed of only non-neuronal elements and cpRNFL from the temporal hemiretina were estimated in the average and 12 sector-cpRNFL thicknesses using regression analysis.
Results
The base level in the average cpRNFL thickness was 71.2 µm in eyes with BA, which corresponded to 70% of average thickness of normal controls. However, the estimated base level of 12 sector-cpRNFL thicknesses represented the unique distribution pattern, in which base level-thickness localised at the 1 o'clock and 5 o'clock sectors was extensively reduced, with an even distribution of base levels at other sectors.
Conclusions
The RNFL originating from the nasal hemiretina is estimated to enter into the optic disc predominantly at the 1 o'clock and 5 o'clock angles.
MeSH Terms
Shields Classification
Key Concepts3
The base level in the average circumpapillary retinal nerve fibre layer (cpRNFL) thickness was 71.2 µm in 53 eyes with band atrophy (BA) due to chiasmal lesions, which corresponded to 70% of the average thickness of normal controls.
The estimated base level of 12 sector-cpRNFL thicknesses in 53 eyes with band atrophy (BA) due to chiasmal lesions represented a unique distribution pattern, with base level-thickness extensively reduced at the 1 o'clock and 5 o'clock sectors and an even distribution of base levels at other sectors.
The retinal nerve fibre layer (RNFL) originating from the nasal hemiretina is estimated to enter into the optic disc predominantly at the 1 o'clock and 5 o'clock angles based on evaluation of circumpapillary retinal nerve fibre layer (cpRNFL) thickness in 53 eyes with band atrophy (BA) accompanying temporal hemianopia due to chiasmal damage.
Related Articles5
Evaluation of visual function and OCT parameters in ethambutol-induced optic neuropathy: a longitudinal study.
Cohort StudyPrimary Visual Pathway Changes in Individuals With Chronic Mild Traumatic Brain Injury.
Case-Control StudyEvaluating glaucoma in myopic eyes: Challenges and opportunities.
ReviewRetinal Perfusion and Injury in Sepsis and after Major Surgery.
Observational StudyComparison of structure-function correlation among IMO visual function analyser and Humphrey field analyser.
Cross-Sectional StudyIs this article assigned to the wrong chapter(s)? Let us know.