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Surv OphthalmolDecember 20249 citations

Evaluating glaucoma in myopic eyes: Challenges and opportunities.

Jiravarnsirikul Anuwat, Belghith Akram, Rezapour Jasmin, Bowd Christopher, Moghimi Sasan, Jonas Jost B, Christopher Mark, Fazio Massimo A, Yang Hongli, Burgoyne Claude F


AI Summary

Diagnosing glaucoma in myopic eyes is challenging due to structural and visual field confounds, requiring careful interpretation of standard diagnostic tests for effective patient management.

Abstract

The increasing global prevalence of myopia presents a significant public health concern, and growing evidence has demonstrated that myopia is a major risk factor for the development of open-angle glaucoma. Therefore, timely detection and management of glaucoma in myopic patients are crucial; however, identifying the structural alterations of glaucoma in the optic nerve head (ONH) and retinal tissues of myopic eyes using standard diagnostic tools such as fundus photography, optical coherence tomography (OCT), and OCT angiography (OCTA) presents challenges. Additionally, myopia-related perimetric defects can be confounded with glaucoma-related defects. We comprehensively examine the challenges encountered in evaluating glaucoma in myopic eyes through various diagnostic tools, including fundus photography, OCT of the ONH, retinal nerve fiber layer, and macular ganglion cell layer, OCTA, and perimetry. We also explore potential opportunities to address these challenges, providing insights for clinicians to effectively manage myopic glaucoma patients in clinical practice.


MeSH Terms

HumansMyopiaTomography, Optical CoherenceOptic DiskRetinal Ganglion CellsVisual FieldsNerve FibersGlaucoma, Open-AngleVisual Field TestsIntraocular PressureGlaucoma

Key Concepts4

Myopia is a major risk factor for the development of open-angle glaucoma.

EpidemiologyReviewn=Not applicableCh10Ch12

Identifying structural alterations of glaucoma in the optic nerve head (ONH) and retinal tissues of myopic eyes using standard diagnostic tools such as fundus photography, optical coherence tomography (OCT), and OCT angiography (OCTA) presents challenges.

DiagnosisReviewn=Not applicableCh4Ch5

Myopia-related perimetric defects can be confounded with glaucoma-related defects.

DiagnosisReviewn=Not applicableCh6

Challenges in evaluating glaucoma in myopic eyes through various diagnostic tools, including fundus photography, OCT of the ONH, retinal nerve fiber layer, and macular ganglion cell layer, OCTA, and perimetry, are comprehensively examined.

MethodologyReviewn=Not applicableCh4Ch5Ch6

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