Incidence of retinal vein occlusion in open-angle glaucoma: a nationwide, population-based study using the Korean Health Insurance Review and Assessment Database.
Na Kyeong Ik, Jeoung Jin Wook, Kim Young Kook, Lee Won June, Park Ki Ho
AI Summary
This study found open-angle glaucoma patients have a significantly higher risk of retinal vein occlusion (3.27 times), highlighting the need for vigilance in this patient group.
Abstract
Importance
We determined the association between retinal vein occlusion (RVO) and open-angle glaucoma (OAG) in a Korean population by reviewing a dataset obtained from the Korean Health Insurance Review and Assessment (HIRA).
Background
To compare the RVO incidence for OAG patients with that for the general population in order to determine the association between RVO and OAG.
Design
Nationwide population-based retrospective study.
Participants
HIRA data for 2011 through 2015.
Methods
The HIRA data for 2011 through 2015 was analysed in order to determine the incidence rates of RVO in the general population and in OAG patients. The standardized incidence ratios (SIRs) of RVO for OAG patients were determined with respect to the age- and gender-matched general population.
Main outcome measures
SIRs of RVO.
Results
The RVO incidence rate for the general population during the 4-year study period (2012-2015) was 74.16 per 100 000 person-years (95% confidence interval [CI], 73.79-74.54). A total of 272 143 OAG patients were identified in 2011 as the population at risk. The RVO incidence rate for the OAG patients was 528.95 per 100 000 person-years (95% CI, 515.46-542.79). The expected incidences of RVO in the OAG patients were 1760.66 during the 4-year study period. On the other hand, the observed incidences of RVO were 5758. The SIR of RVO for OAG patients in reference to the general population was 3.27 (95% CI, 3.19-3.35).
Conclusions and relevance: The RVO incidence rate for OAG patients is significantly higher than that for the general population.
MeSH Terms
Shields Classification
Key Concepts5
The incidence rate of retinal vein occlusion (RVO) for open-angle glaucoma (OAG) patients in Korea was 528.95 per 100,000 person-years (95% CI, 515.46-542.79) during the 4-year study period (2012-2015).
The standardized incidence ratio (SIR) of retinal vein occlusion (RVO) for open-angle glaucoma (OAG) patients in reference to the general Korean population was 3.27 (95% CI, 3.19-3.35).
The retinal vein occlusion (RVO) incidence rate for open-angle glaucoma (OAG) patients in Korea is significantly higher than that for the general Korean population.
The incidence rate of retinal vein occlusion (RVO) for the general Korean population during the 4-year study period (2012-2015) was 74.16 per 100,000 person-years (95% confidence interval [CI], 73.79-74.54).
A total of 272,143 open-angle glaucoma (OAG) patients were identified in 2011 as the population at risk.
Related Articles5
Glaucomatous disease in patients with normal pressure hydrocephalus.
Case-Control StudyPrevalence of open-angle glaucoma, glaucoma suspect, and ocular hypertension in thyroid-related immune orbitopathy.
Cross-Sectional StudyIn Reply: Incidence of Open-angle Glaucoma in Newly Diagnosed Retinal Vein Occlusion: A Nationwide Population-based Study.
Cohort StudyDetection of Glaucoma and Its Association With Diabetic Retinopathy in a Diabetic Retinopathy Screening Program.
Cross-Sectional StudyGlaucoma in patients with sleep apnea.
Observational StudyIs this article assigned to the wrong chapter(s)? Let us know.