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Idebenone prevents human optic nerve head astrocytes from oxidative stress, apoptosis, and senescence by stabilizing BAX/Bcl-2 ratio.
Kernt Marcus, Arend Nicole, Buerger Alexandra, Mann Thomas, Haritoglou Christos, Ulbig Michael W et al.
J GlaucomaMay 201324 citationsBasic Science
Idebenone protected optic nerve head astrocytes from oxidative stress, apoptosis, and senescence in vitro by balancing BAX/Bcl-2. This suggests idebenone could help prevent glaucomatous neurodegeneration.