Kampik Anselm

Reznicek Lukas, Muth Daniel, Kampik Anselm, Neubauer Aljoscha S, Hirneiss Christoph

This study found a novel Scheimpflug device (Corvis ST) accurately measures IOP and CCT in healthy, OHT, and glaucoma patients, showing good agreement with standard methods and excellent repeatability.

Kernt Marcus, Arend Nicole, Buerger Alexandra, Mann Thomas, Haritoglou Christos, Ulbig Michael W et al.

Idebenone protected optic nerve head astrocytes from oxidative stress, apoptosis, and senescence in vitro by balancing BAX/Bcl-2. This suggests idebenone could help prevent glaucomatous neurodegeneration.

Messmer Elisabeth M, Valet Véronique M, Kampik Anselm

This study found distinct basement membrane zone component differences between normal conjunctiva, skin, and glaucoma conjunctiva, with glaucoma showing increased laminin β1 and γ2. These variations may explain ocular disease susceptibility.

Schumann Ricarda G, Eibl Kirsten H, Zhao Fei, Scheerbaum Martin, Scheler Renate, Schaumberger Markus M et al.

Studying macular hole ILMs, researchers found glial cells and hyalocytes are key players in epiretinal proliferation, suggesting their crucial role in macular hole development and progression.

Hirneiss Christoph, Neubauer Aljoscha S, Yu Alice, Kampik Anselm, Kernt Marcus

This study found corneal hysteresis (CH) depends on IOP, not corneal resistance factor. In unilateral glaucoma, CH differences between eyes disappear when corrected for IOP, suggesting corneal biomechanics aren't inherently different.

Nentwich Martin M, Remy Matthias, Haritoglou Christos, Kampik Anselm

Yu Alice L, Brummeisl Wolfgang, Schaumberger Markus, Kampik Anselm, Welge-Lussen Ulrich

This 5-year study found vitrectomy, regardless of lens status, does not increase the risk of developing open-angle glaucoma or ocular hypertension, reassuring for patients undergoing this common surgery.

Kreutzer Thomas C, Al Saeidi Rashid, Kampik Anselm, Grueterich Martin

This study monitored real-time intraocular pressure during cataract surgery. Both standard and microcoaxial phacoemulsification maintained safe IOP profiles, suggesting real-time monitoring can prevent excessive pressure.

von Jagow Burkhard, Höing Anna, Gandorfer Arnd, Rudolph Günther, Kohnen Thomas, Kampik Anselm et al.

ICG-assisted macular surgery was studied long-term. It was linked to persistent visual field defects, color vision issues, and optic nerve atrophy, suggesting potential long-term neurotoxicity.

Thaler Sebastian, Schuettauf Frank, Fiedorowicz Michal, Messias Andre, Schatz Andreas, Choragiewicz Tomasz J et al.

Methyl blue and aniline blue dyes showed good retinal biocompatibility up to 0.2% in rats, suggesting potential for safe intraocular surgery, though 2% was toxic.

Yu Alice L, Moriniere Jerome, Birke Marco, Neumann Carolin, Fuchshofer Rudolf, Kampik Anselm et al.

This study found that TGF-beta2 and H2O2, which reactivate optic nerve head astrocytes, increase Hsp32 and Hsp47 expression. This suggests these proteins are involved in astrocyte stress responses in glaucoma.

Yu Alice L, Fuchshofer Rudolf, Birke Marco, Kampik Anselm, Bloemendal Hans, Welge-Lüssen Ulrich

Oxidative stress and TGF-beta2 increase Hsp27 in optic nerve head astrocytes via p38MAP kinase. Reducing these factors might protect the optic nerve in glaucoma.

Yu Alice L, Fuchshofer Rudolf, Kampik Anselm, Welge-Lüssen Ulrich

This study found oxidative stress induces glaucomatous changes in trabecular meshwork cells, which prostaglandin analogues can reduce. This suggests PGAs may protect TM cells, potentially slowing glaucoma progression.

Kernt Marcus, Neubauer Aljoscha Steffen, Ulbig Michael W, Kampik Anselm, Welge-Lüssen Ulrich

This study found intravitreal moxifloxacin is safe for retinal and optic nerve cells up to 150 microg/mL. This suggests its potential for safe endophthalmitis treatment at this concentration.

Haritoglou Christos, Strauss Rupert, Priglinger Siegfried G, Kreutzer Thomas, Kampik Anselm

Bromophenol blue safely and effectively stains vitreous and posterior hyaloid during vitrectomy for macular holes and retinal detachments, improving visualization for complete removal and better surgical outcomes.

Miño de Kaspar Herminia, Kreutzer Thomas C, Aguirre-Romo Israel, Ta Christopher N, Dudichum Julia, Bayrhof Markus et al.

Preoperative levofloxacin combined with povidone-iodine significantly reduced conjunctival bacteria before intraocular surgery, improving infection prophylaxis.

Haritoglou Christos, Kook Daniel, Neubauer Aljoscha, Wolf Armin, Priglinger Siegfried, Strauss Rupert et al.

Intravitreal bevacizumab for diffuse diabetic macular edema showed short-term retinal thickness reduction and visual acuity improvement, even in previously treated cases, suggesting potential for this treatment.

Priglinger Siegfried G, Alge Claudia S, Kook Daniel, Thiel Martin, Schumann Ricarda, Eibl Kirsten et al.

This study found tissue transglutaminase (tTgase) is active in failed glaucoma surgery blebs, stimulated by TGF-beta2. Targeting tTgase could prevent scarring and improve surgical outcomes.

Schuettauf Frank, Haritoglou Christos, May Christian A, Rejdak Robert, Mankowska Anna, Freyer Wolfgang et al.

This rat study found novel dyes ICG, E68, and CB caused retinal toxicity, including ganglion cell loss, while BPB and LGSF appeared safe, highlighting the need for further safety evaluation.

Hirneiss Christoph, Neubauer Aljoscha S, Kampik Anselm, Schönfeld Carl-Ludwig

This study compared three eye drops after cataract surgery, finding ketorolac effectively controlled inflammation without steroid-induced IOP spikes, while prednisolone offered best surface inflammation control and patient comfort.

Eibl Kirsten H, Banas Bernhard, Kook Daniel, Ohlmann Anne V, Priglinger Siegfried, Kampik Anselm et al.

Alkylphosphocholines (APCs) effectively inhibited human Tenon fibroblast proliferation, migration, and contraction at non-toxic levels. This suggests APCs could be a new therapeutic option to prevent scarring in glaucoma filtration surgery.

Haritoglou Christos, Gandorfer Arnd, Schaumberger Markus, Priglinger Siegfried G, Mueller Arthur J, Gass Carolin A et al.

This study found low-concentration (0.02%) trypan blue for macular pucker surgery caused no retinal damage or functional difference, but higher concentrations (0.15-0.25%) did. This suggests safer use at lower concentrations.

Mueller Arthur J, Freeman William R, Schaller Ulrich C, Kampik Anselm, Folberg Robert

Confocal ICG angiography of small choroidal melanocytic tumors revealed complex microcirculation patterns strongly predict faster tumor growth, offering a novel clinical predictor for management.

Haritoglou Christos, Gandorfer Arnd, Gass Carolin A, Schaumberger Markus, Ulbig Michael W, Kampik Anselm

ICG-assisted macular hole surgery may cause retinal damage by altering the cleavage plane, potentially leading to less visual improvement and unexpected visual field defects.

Haritoglou Christos, Gass Carolin A, Schaumberger Markus, Gandorfer Arnd, Ulbig Michael W, Kampik Anselm

Long-term follow-up of macular hole surgery with ILM peeling showed high closure rates and significant visual improvement, confirming its effectiveness for restoring vision and highlighting its lasting benefit.