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Aschard Hugues

ORCIDOpenAlex5 articles in GJC

5 articles in GJC

2.

Statin Use in Relation to Intraocular Pressure, Glaucoma, and Ocular Coherence Tomography Parameters in the UK Biobank.

Kim Jihye, Kennedy Neary Marianne T, Aschard Hugues, Palakkamanil Mathew M, Do Ron, Wiggs Janey L et al.

Invest Ophthalmol Vis SciMay 20229 citationsCross-Sectional Study

This study found statin use was not associated with lower IOP or glaucoma risk, nor did it significantly impact retinal nerve fiber or ganglion cell layer thickness, suggesting no protective role for glaucoma.

3.

The Association between Serum Lipids and Intraocular Pressure in 2 Large United Kingdom Cohorts.

Madjedi Kian M, Stuart Kelsey V, Chua Sharon Y L, Luben Robert N, Warwick Alasdair, Pasquale Louis R et al.

OphthalmologyApr 20220 citationsCross-Sectional Study

This study found higher total, HDL, and LDL cholesterol are associated with slightly higher intraocular pressure. This suggests lipid management might influence glaucoma risk, warranting further investigation into causality.

4.

Intraocular Pressure, Glaucoma, and Dietary Caffeine Consumption: A Gene-Diet Interaction Study from the UK Biobank.

Kim Jihye, Aschard Hugues, Kang Jae H, Lentjes Marleen A H, Do Ron, Wiggs Janey L et al.

OphthalmologyDec 202058 citationsCross-Sectional Study

Studying caffeine intake and glaucoma, researchers found high genetic risk for elevated IOP combined with significant caffeine consumption increased IOP and glaucoma prevalence, suggesting a gene-diet interaction is clinically relevant.

5.

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets.

Bailey Jessica N Cooke, Gharahkhani Puya, Kang Jae H, Butkiewicz Mariusz, Sullivan David A, Weinreb Robert N et al.

Invest Ophthalmol Vis SciFeb 201814 citationsCase-Control Study

Testosterone pathway genetic variations were consistently associated with high-tension primary open-angle glaucoma, particularly in men, suggesting a potential sex-specific genetic risk factor for this severe glaucoma subtype.

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