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C677T variant in the methylentetrahydrofolate reductase gene is a genetic risk factor for primary open-angle glaucoma.
Jünemann Anselm G M, von Ahsen Nico, Reulbach Udo, Roedl Johannes, Bönsch Dominikus, Kornhuber Johannes et al.
Am J OphthalmolApr 200556 citationsCase-Control Study
This study found the MTHFR C677T gene variant is a genetic risk factor for primary open-angle glaucoma, suggesting its role in disease development.