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Brescia Lorenza

๐Ÿ‡จ๐Ÿ‡ณ University of Chieti-Pescara
ORCIDOpenAlex13 articles in GJC

13 articles in GJC

1.

A deep learning approach to investigate the filtration bleb functionality after glaucoma surgery: a preliminary study.

Mastropasqua Leonardo, Agnifili Luca, Brescia Lorenza, Figus Michele, Posarelli Chiara, Oddone Francesco et al.

Graefes Arch Clin Exp OphthalmolAug 20230 citationsCross-Sectional Study

This study used deep learning on slit-lamp images to distinguish functioning from failed glaucoma surgery blebs. The model achieved good accuracy, potentially aiding clinicians in managing post-operative patients.

3.

Conjunctival thickness as a predictive imaging biomarker for the glaucoma filtration surgery outcome: An optical coherence tomography study.

Mastropasqua Leonardo, Brescia Lorenza, Oddone Francesco, Sacchi Matteo, Aloia Raffaella, Totta Michele et al.

Clin Exp OphthalmolSep 20208 citationsRetrospective Study

Preoperative OCT-measured conjunctival thickness and reflectivity predict glaucoma filtration surgery outcome. Thinner conjunctiva and higher reflectivity correlate with surgical failure, serving as potential biomarkers to estimate risk.

4.

Structural imaging of conjunctival filtering blebs in XEN gel implantation and trabeculectomy: a confocal and anterior segment optical coherence tomography study.

Sacchi Matteo, Agnifili Luca, Brescia Lorenza, Oddone Francesco, Villani Edoardo, Nucci Paolo et al.

Graefes Arch Clin Exp OphthalmolMay 202026 citationsCross-Sectional Study

XEN gel implantation blebs are flatter, thinner, and have more epithelial cysts than trabeculectomy blebs, suggesting different filtering mechanisms and surgical impacts on conjunctival tissue.

8.

Meibomian Gland Features and Conjunctival Goblet Cell Density in Glaucomatous Patients Controlled With Prostaglandin/Timolol Fixed Combinations: A Case Control, Cross-sectional Study.

Agnifili Luca, Mastropasqua Rodolfo, Fasanella Vincenzo, Brescia Lorenza, Scatena Barbara, Oddone Francesco et al.

J GlaucomaApr 201827 citationsCase-Control Study

This study found that preservative-free prostaglandin/timolol fixed combinations are less toxic to meibomian glands and goblet cells in glaucoma patients, reducing ocular surface damage.

9.

In Vivo Confocal Imaging of the Conjunctiva as a Predictive Tool for the Glaucoma Filtration Surgery Outcome.

Mastropasqua Rodolfo, Fasanella Vincenzo, Brescia Lorenza, Oddone Francesco, Mariotti Cesare, Di Staso Silvio et al.

Invest Ophthalmol Vis SciMay 201742 citationsCase-Control Study

Preoperative conjunctival imaging (IVCM) revealed that lower dendritic cell density and higher goblet cell density predict better glaucoma filtration surgery outcomes, offering a clinical tool for success prediction.

10.

In Vivo Distribution of Corneal Epithelial Dendritic Cells in Patients With Glaucoma.

Mastropasqua Rodolfo, Agnifili Luca, Fasanella Vincenzo, Lappa Andrea, Brescia Lorenza, Lanzini Manuela et al.

Invest Ophthalmol Vis SciNov 201646 citationsCase-Control Study

This study found corneal dendritic cells are significantly increased in medically controlled glaucoma patients, particularly with more medications or preservatives, suggesting their role in glaucoma-related ocular surface disease.

12.

Uveo-scleral outflow pathways after ultrasonic cyclocoagulation in refractory glaucoma: an anterior segment optical coherence tomography and in vivo confocal study.

Mastropasqua Rodolfo, Agnifili Luca, Fasanella Vincenzo, Toto Lisa, Brescia Lorenza, Di Staso Silvio et al.

Br J OphthalmolFeb 201643 citationsClinical Trial

UCCC for refractory glaucoma increases scleral hyporeflective spaces and conjunctival microcysts, suggesting enhanced trans-scleral aqueous outflow contributes to IOP reduction.

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