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Frezzotti Paolo

๐Ÿ‡จ๐Ÿ‡ณ University of Siena
ORCIDOpenAlex13 articles in GJC

13 articles in GJC

2.

Macular versus nerve fibre layer versus optic nerve head imaging for diagnosing glaucoma at different stages of the disease: Multicenter Italian Glaucoma Imaging Study.

Michelessi Manuele, Riva Ivano, Martini Enrico, Figus Michele, Frezzotti Paolo, Agnifili Luca et al.

Acta OphthalmolOct 20180 citationsCase-Control Study

This study found that optic nerve head (MRW) and nerve fiber layer (pRNFL) imaging are superior to macular OCT for diagnosing early glaucoma, offering better diagnostic accuracy.

5.

Circadian intraocular pressure patterns in healthy subjects, primary open angle and normal tension glaucoma patients with a contact lens sensor.

Agnifili Luca, Mastropasqua Rodolfo, Frezzotti Paolo, Fasanella Vincenzo, Motolese Ilaria, Pedrotti Emilio et al.

Acta OphthalmolApr 2014113 citationsObservational Study

This study found glaucoma patients, especially POAG, have higher nocturnal IOP peaks than healthy subjects. Continuous 24-hour monitoring is crucial for comprehensive glaucoma management, as diurnal IOP doesn't predict nocturnal patterns.

6.

In vivo confocal microscopy of conjunctiva in preservative-free timolol 0.1% gel formulation therapy for glaucoma.

Frezzotti Paolo, Fogagnolo Paolo, Haka Gentiana, Motolese Ilaria, Iester Michele, Bagaglia Simone A et al.

Acta OphthalmolMar 201432 citationsRandomized Controlled Trial

This study found preservative-free timolol gel causes fewer conjunctival goblet cell changes and less dry eye than preserved timolol, highlighting its benefit for long-term glaucoma treatment adherence.

8.

Association between primary open-angle glaucoma (POAG) and WDR36 sequence variance in Italian families affected by POAG.

Frezzotti Paolo, Pescucci Chiara, Papa Filomena Tiziana, Iester Michele, Mittica Vincenzo, Motolese Ilaria et al.

Br J OphthalmolMay 201117 citationsObservational Study

WDR36 gene variants were studied in Italian POAG families. Findings suggest WDR36 is a rare cause of glaucoma in this population, implying limited clinical relevance for routine genetic screening.

12.

An in vivo confocal microscopy analysis of effects of topical antiglaucoma therapy with preservative on corneal innervation and morphology.

Martone Gianluca, Frezzotti Paolo, Tosi Gian Marco, Traversi Claudio, Mittica Vincenzo, Malandrini Alex et al.

Am J OphthalmolApr 2009180 citationsRetrospective Study

Preservative-containing glaucoma drops significantly damage the corneal surface and nerves compared to preservative-free drops. This highlights the need for less toxic treatments to improve patient comfort and adherence.

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