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Burke Alyce E

🇴🇲 Johns Hopkins University
ORCIDOpenAlex3 articles in GJC

3 articles in GJC

1.

Macular Edema Ranibizumab versus Intravitreal Anti-inflammatory Therapy Trial: 24-Week Outcomes of Uveitic Macular Edema Re-treatment.

Gonzales John, Acharya Nisha R, Sugar Elizabeth A, Burke Alyce E, Vitale Albert T, Gupta Vishali et al.

OphthalmologyNov 20242 citationsRandomized Controlled Trial

This study found the dexamethasone implant was most effective for uveitic macular edema over 24 weeks compared to ranibizumab or methotrexate, offering a superior treatment option despite side effects.

2.

Cataract Surgery in Patients With Uveitis Treated With Systemic Therapy in the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study: Risk Factors and Outcomes.

Jabs Douglas A, Sugar Elizabeth A, Burke Alyce E, Altaweel Michael M, Dunn James P, Gangaputra Sapna et al.

Am J OphthalmolJul 20234 citationsCohort Study

Uveitis patients on systemic therapy face high, ongoing cataract surgery risk, especially with age or topical steroids. Surgery generally yields good visual outcomes, but risk factors need careful monitoring.

3.

Intravitreal Therapy for Uveitic Macular Edema-Ranibizumab versus Methotrexate versus the Dexamethasone Implant: The MERIT Trial Results.

Acharya Nisha R, Vitale Albert T, Sugar Elizabeth A, Holbrook Janet T, Burke Alyce E, Thorne Jennifer E et al.

OphthalmologyJun 202319 citationsRandomized Controlled Trial

The MERIT trial found dexamethasone implants are superior to methotrexate and ranibizumab for uveitic macular edema at 12 weeks, despite a higher risk of treatable IOP elevation.

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