Thorne Jennifer E

Chu David S, Tsui Edmund, Rifkin Lana M, Palestine Alan G, Rich Cadmus, Thorne Jennifer E et al.

Dazdotuftide showed noninferiority for uveitis flare/pain control versus prednisolone, with significantly fewer IOP elevations. This steroid-sparing option could benefit patients prone to steroid-induced IOP, despite less complete cell resolution.

Vienne-Jumeau Aliénor, Memmi Caroline, Kecili Souhila, Loeliger Jordan, Thorne Jennifer E, Monnet Dominique et al.

This study found severe retinal depigmentation in 5.1% of Birdshot chorioretinitis patients, indicating chronic disease and significantly poorer long-term vision, including faster decline and higher risk of complications.

Ferreira de Moura Thomas, Enjalbert Aurélie, Monnet Dominique, Kecili Souhila, Imikerene Linda, Loeliger Jordan et al.

This study found peripapillary atrophy is almost universal in birdshot chorioretinitis, worsening with disease duration and age, and correlating with poorer vision, highlighting its clinical relevance as a disease progression marker.

Marshall Rayna F, Lee Daniel, Thorne Jennifer E, Kaleem Mona, Berkenstock Meghan K

This study found uveitic glaucoma incidence/prevalence decreased since 2013, but anterior and intermediate uveitis patients still face the highest risk, highlighting the need for vigilant monitoring in these groups.

Gonzales John, Acharya Nisha R, Sugar Elizabeth A, Burke Alyce E, Vitale Albert T, Gupta Vishali et al.

This study found the dexamethasone implant was most effective for uveitic macular edema over 24 weeks compared to ranibizumab or methotrexate, offering a superior treatment option despite side effects.

Smith Justine R, Thorne Jennifer E, Flaxel Christina J, Jain Nieraj, Kim Stephen J, Maguire Maureen G et al.

This review found periocular and intraocular corticosteroids effectively treat noninfectious uveitic macular edema, improving vision and structure, though with risks like elevated eye pressure and cataracts.

Thng Zheng Xian, Putera Ikhwanuliman, Testi Ilaria, Chan Kevin, Westcott Mark, Chee Soon-Phaik et al.

Global experts defined key diagnostic features for HSV/VZV anterior uveitis, favoring valacyclovir for treatment initiation. This helps standardize care and improve patient outcomes.

Acharya Nisha R, Vitale Albert T, Sugar Elizabeth A, Holbrook Janet T, Burke Alyce E, Thorne Jennifer E et al.

The MERIT trial found dexamethasone implants are superior to methotrexate and ranibizumab for uveitic macular edema at 12 weeks, despite a higher risk of treatable IOP elevation.

Liberman Paulina, Burkholder Bryn M, Thorne Jennifer E, Berkenstock Meghan K

Difluprednate effectively treated non-infectious anterior scleritis, especially with higher initial dosing, showing good resolution rates and a tolerable side effect profile, making it a viable therapeutic option.

Böni Christian, Thorne Jennifer E, Spaide Richard F, Ostheimer Trucian A, Sarraf David, Levinson Ralph D et al.

This study found common fundus autofluorescence (FAF) abnormalities, especially hypoautofluorescence, in birdshot chorioretinitis patients. These FAF changes indicate retinal pigment epithelium dysfunction and correlate with worse vision.

Daniel Ebenezer, Pistilli Maxwell, Kothari Srishti, Khachatryan Naira, Kaçmaz R Oktay, Gangaputra Sapna S et al.

This study found ocular hypertension is common in noninfectious uveitis patients, with corticosteroids and inflammation being major risk factors. Close monitoring and careful management are crucial to prevent vision loss.

Moradi Ahmadreza, Stroh Inna G, Reddy Ashvini K, Hornbeak Dana M, Leung Theresa G, Burkholder Bryn M et al.

This study found severe uveitis increases hypotony risk in JIA-associated uveitis, while immunosuppression reduces it. Aggressive inflammation control may prevent vision-threatening hypotony.

Ashraf Davin C, May K Patrick, Holland Gary N, Van Natta Mark L, Wu Albert W, Thorne Jennifer E et al.

HIV-NRD significantly lowers vision-specific quality of life in people with AIDS, even with good acuity. This highlights the importance of assessing contrast sensitivity and QOL in HIV patients.

Kothari Srishti, Foster C Stephen, Pistilli Maxwell, Liesegang Teresa L, Daniel Ebenezer, Sen H Nida et al.

This study found that high eye pressure is common in children with non-infectious uveitis, often linked to local steroid use and contralateral eye pressure, necessitating close monitoring.

Jabs Douglas A, Drye Lea, Van Natta Mark L, Thorne Jennifer E, Holland Gary N

This study found HIV neuroretinal disorder is common in AIDS patients, increasing mortality and visual impairment risk, highlighting its significant long-term impact despite treatment.

Burkholder Bryn M, Wang Jiangxia, Dunn James P, Nguyen Quan D, Thorne Jennifer E

FA implants effectively control uveitis, but birdshot chorioretinitis patients showed significantly higher intraocular pressure increases and more glaucoma surgeries than other uveitis types.

Friedman David S, Holbrook Janet T, Ansari Husam, Alexander Judith, Burke Alyce, Reed Susan B et al.

This study found uveitis patients treated with FA implants had a 4x higher risk of elevated IOP and glaucoma than those on systemic therapy, highlighting the need for aggressive IOP monitoring.

Daniel Ebenezer, Pistilli Maxwell, Pujari Siddharth S, Kaçmaz R Oktay, Nussenblatt Robert B, Rosenbaum James T et al.

This study found hypotony is rare in noninfectious uveitis, but cataract surgery significantly increases risk, especially with anterior segment inflammation, highlighting the need for careful surgical planning and inflammation control.

Kalyani Partho S, Fawzi Amani A, Gangaputra Sapna, van Natta Mark L, Hubbard Larry D, Danis Ronald P et al.

This study found that narrower retinal arteriole-to-venule ratios in AIDS patients were associated with worse visual fields, suggesting HIV-related retinal vasculopathy contributes to vision loss.

Leder Henry A, Jabs Douglas A, Galor Anat, Dunn James P, Thorne Jennifer E

Periocular triamcinolone injections resolved uveitic cystoid macular edema in over half of patients, improving vision, but recurrence was common, highlighting its role as an effective but temporary treatment.

Thorne Jennifer E, Van Natta Mark L, Jabs Douglas A, Duncan Jacque L, Srivastava Sunil K

This study found visual field loss in CMV retinitis patients is 6x lower with HAART, and immune recovery significantly reduces this risk, highlighting the importance of immune status.

Lim Lyndell L, Scarborough John D, Thorne Jennifer E, Graham Elizabeth, Kempen John H, Mackensen Friederike et al.

This study found uveitis, often chronic and bilateral with sight-threatening complications like glaucoma, may be an extrahepatic feature of autoimmune hepatitis, requiring systemic immunosuppression.

Kim Stephen J, Adams Neal A, Toma Hassanain S, Belair Marie-Lyne, Thorne Jennifer E, Green W Richard et al.

This rabbit study found high-dose intravitreal ketorolac and diclofenac were toxic, but lower doses (3000 µg ketorolac, 300 µg diclofenac) were safe, suggesting potential steroid-sparing alternatives for ocular inflammation.

Thorne Jennifer E, Jabs Douglas A, Kedhar Sanjay R, Peters George B, Dunn James P

Birdshot chorioretinopathy often causes visual field loss, but immunosuppressive therapy may help reverse this damage, highlighting its potential clinical benefit.

Gilson Marta M, Bressler Neil M, Jabs Douglas A, Solomon Sharon D, Thorne Jennifer E, Wilson David J

This study found that adding periocular triamcinolone to photodynamic therapy for AMD-related CNV did not improve leakage or vision, but increased intraocular pressure risk, suggesting no clinical benefit.