Friedman David S

Fujita Asahi, Zebardast Nazlee, Lorch Alice C, Miller Joan W, Friedman David S

This study found that MIGS, trabeculectomy, and tube shunts for secondary glaucoma in young adults had ~50% failure at two years, varying by glaucoma subtype. Outcomes suggest tailored surgical approaches are crucial.

Fujita Asahi, Moradi Mousa, Shah Rishi, Elze Tobias, Zebardast Nazlee, Friedman David S

This study found that over a quarter of eyes with pseudoexfoliation (PXF), even without high eye pressure, developed glaucoma within 4 years, highlighting the high risk in PXF.

Huang Andy S, Fam Anthony, Zhao Hetince, Paulescu Nicole, Fabczak-Kubicka Anna, Wiggs Janey L et al.

ChatGPT diagnosed glaucoma with high sensitivity (96%) and reasonable specificity (83.7%) from visual field/OCT data. Its performance was consistent across diverse ancestries and genetic risks, suggesting LLMs could be unbiased screening tools for early glaucoma detection.

Wang Ziyao, Xue Can Can, Li Yiman, Wu You, Pan Zhe, Li Fan et al.

Global OAG prevalence will nearly triple by 2060, reaching 192.7 million, largely driven by the myopia epidemic. This necessitates myopia prevention and targeted OAG screening, especially in younger populations and high-myopia regions.

Hong Kendra L, Xu Benjamin Y, Wang Wei, Cho Austin, Foster Paul J, Jiang Yuzhen et al.

Nasal iridotrabecular contact (ITC) and greater ITC length on AS-OCT predict PACS to PAC progression. Qualitative ITC assessment offers a practical, accessible method for identifying high-risk PACS eyes, streamlining clinical risk stratification.

Zhang Yapei, Shi Min, Chung In Young, Liebman Daniel L, Barna Laura E, Pasquale Louis R et al.

LLaMA 2-70B shows promise for patient-friendly glaucoma summaries, achieving 66-70% accuracy. Better for suspects, it excels in targeted questions (80-91% accuracy). LLMs could enhance patient communication and health literacy in ophthalmology.

Foster Paul J, Aung Tin, Friedman David S

Servillo Andrea, Tun Tin A, Yoo Chungkwon, Kumar Rajesh S, Baskaran Mani, Nongpiur Monisha E et al.

This study found laser iridotomy sustained angle widening in two-thirds of patients. Persistent angle closure, seen in 33%, was predicted by a thicker iris and younger age, guiding personalized treatment.

Fujita Asahi, Elze Tobias, Zhao Yan, Lorch Alice C, Miller Joan W, Friedman David S et al.

This study found pseudoexfoliation glaucoma patients require surgery more often and experience more post-operative complications than primary open-angle glaucoma, highlighting its aggressive nature and need for close monitoring.

Lokhande Anagha, Aziz Kanza, Fujita Asahi, Pasquale Louis R, Shen Lucy Q, Friedman David S et al.

This study found most glaucoma surgeries, especially complex ones like trabeculectomy, occur in urban centers, often requiring significant patient travel. This highlights disparities in surgical access, particularly for rural patients.

Hong Kendra L, Xu Benjamin Y, Wang Wei, Cho Austin, Kistler Natalie M, Foster Paul J et al.

Short-term changes in lens vault and angle width predict long-term angle closure progression in PACS eyes, enhancing risk assessment beyond baseline biometrics for earlier intervention.

Fujita Asahi, Vu Daniel M, Rothman Adam L, Friedman David S, Zebardast Nazlee, Chang Ta Chen

Childhood glaucoma surgery failed in nearly half of cases. Younger age, higher initial IOP, and concurrent uveitis predict failure, highlighting the need for early, aggressive management in these complex patients.

Kim Jihye, Kang Jae H, Wiggs Janey L, Zhao Hetince, Li Keva, Zebardast Nazlee et al.

This study found that a genetic risk score for glaucoma predicts higher intraocular pressure and glaucoma prevalence more strongly with increasing age, highlighting age's importance in genetic screening.

Seresirikachorn Kasem, Annopawong Kornkamol, Parivisutt Nucharee, Wanichwecharungruang Boonsong, Friedman David S, Vu Daniel M

For JOAG patients failing primary trabeculectomy, second trabeculectomy and GDDs offer similar success, but second trabeculectomies required fewer medications, guiding treatment choice.

Fujita Asahi, Vu Daniel M, Aziz Kanza, Chang Ta Chen, Chung In Young, Ciociola Elizabeth C et al.

This study found that 1 in 6 childhood glaucoma eyes underwent surgery, nearly all used medication, and treatment varied by glaucoma type, age, and specialist, impacting surgical likelihood.

Wang Qing, Valenzuela Ives A, Harizman Noga, Gorroochurn Prakash, Torres Desiree R, Maruri Stefania C et al.

Community-based glaucoma screening in high-risk populations effectively identified many needing further evaluation. This supports targeted public health screenings to detect glaucoma early in underserved communities.

Eng Kathleen, Zebardast Nazlee, Boland Michael V, Lo Jui-En, Swaminathan Swarup S, Friedman David S et al.

SGLT2 inhibitors significantly lowered glaucoma risk in type 2 diabetes patients compared to other diabetes drugs, suggesting a potential protective effect against both open-angle and angle-closure glaucoma.

Ehrlich Joshua R, Burke-Conte Zeb, Wittenborn John S, Saaddine Jinan, Omura John D, Friedman David S et al.

This study found 2.56% of US adults aged 40+ have glaucoma, disproportionately affecting Black individuals. These updated prevalence estimates are crucial for targeted public health planning.

de Vries Victor A, Hanyuda Akiko, Vergroesen Joëlle E, Do Ron, Friedman David S, Kraft Peter et al.

This study found a glaucoma polygenic risk score significantly improved POAG prediction, raising concordance from 0.75 to 0.82. This tool could enhance screening and identify high-risk individuals for earlier intervention.

Pang Yueyin, Tang Melody, Shi Min, Tian Yu, Luo Yan, Elze Tobias et al.

This study found Black and non-English speaking glaucoma patients experience worse and faster visual field loss, especially in the superior hemifield, highlighting disparities needing targeted screening and outreach.

Banerjee Seema, Mihailovic Aleksandra, Miller Rhonda, E Jian-Yu, Gitlin Laura N, Xiong Yingzi et al.

This study found better home lighting was linked to increased physical activity (steps, cadence) in older adults with glaucoma, suggesting home modifications could boost activity.

Medeiros Felipe A, Malek Davina A, Tseng Henry, Swaminathan Swarup S, Boland Michael V, Friedman David S et al.

This study found intensive, clustered glaucoma testing over 6 months effectively identifies fast progressors. This method is valuable for clinical trials and short-term assessment of high-risk patients.

Goddin Traci-Lin, Yu Haojue, Friedman David S, Owsley Cynthia, Kwon MiYoung

This study found glaucoma patients have significantly worse reading vision in dim light than healthy individuals, highlighting the need for mesopic testing to better assess real-world visual impairment.

Sun Jessica A, Yuan Melissa, Johnson Grace E, Pasquale Louis R, Boland Michael V, Friedman David S et al.

This study found PACG patients had less structural damage but similar functional loss, with PACG showing inferior field loss and POAG superior, aiding differentiated monitoring.

Jayaram Hari, Kolko Miriam, Friedman David S, Gazzard Gus

Glaucoma causes irreversible vision loss, primarily managed by lowering intraocular pressure. While effective, challenges include late diagnosis and limited evidence for many new treatments, highlighting the need for future neuroprotective and personalized therapies.