Tun Tin A

Tun Tin A, Tan Nicholas Y Q, Tan Royston K Y, Syn Yamon Thant, Chan Hiok Hong, Yu Qing Chang et al.

This study linked asymmetrical NTG-OSA to side-sleeping, finding reduced optic nerve head blood flow in the lower eye during side-lying, suggesting a positional role in glaucoma progression.

Chuangsuwanich Thanadet, Nongpiur Monisha E, Braeu Fabian A, Prasad Shimna Clara, Tun Tin A, Thiéry Alexandre et al.

ONH tissue strain significantly improved glaucoma VF defect classification (e.g., superior arcuate, AUC 0.83 to 0.87). Neuroretinal rim strain, particularly inferotemporal, was key, suggesting it's a critical biomechanical biomarker for axonal injury and disease monitoring.

Servillo Andrea, Tun Tin A, Yoo Chungkwon, Kumar Rajesh S, Baskaran Mani, Nongpiur Monisha E et al.

This study found laser iridotomy sustained angle widening in two-thirds of patients. Persistent angle closure, seen in 33%, was predicted by a thicker iris and younger age, guiding personalized treatment.

Sharma Swati, Braeu Fabian A, Chuangsuwanich Thanadet, Tun Tin A, Hoang Quan V, Chong Rachel et al.

This study identified distinct 3D optic nerve head structural patterns in healthy, myopic, and glaucomatous eyes, suggesting these unique signatures can improve glaucoma diagnosis, especially in myopic patients.

Tan Royston K Y, Tun Tin A, Braeu Fabian A, Perera Shamira A, Girard Michaël J A

Computational modeling showed iris crypts can help prevent angle closure by maintaining a wider angle, even with reduced iris permeability. This suggests new treatment targets for high-risk patients.

Porporato Natalia, Xu Benjamin Y, Tan Bingyao, Chang Yu Q, Tun Tin A, Perera Shamira et al.

Novel HP-OCT reliably assesses angle closure, showing excellent reproducibility and good agreement with SS-OCT/gonioscopy, while uniquely visualizing distal outflow pathways, enhancing glaucoma research.

Chuangsuwanich Thanadet, Nongpiur Monisha E, Braeu Fabian A, Tun Tin A, Thiery Alexandre, Perera Shamira et al.

This study found that combining optic nerve structure with biomechanical data (IOP-induced tissue strains) significantly improves prediction of visual field loss in glaucoma, highlighting biomechanics' clinical importance for functional prognosis.

Chuangsuwanich Thanadet, Tun Tin A, Braeu Fabian A, Chong Rachel S, Wang Xiaofei, Ho Ching-Lin et al.

This study found that highly myopic glaucoma, pathologic myopia, and staphyloma eyes show greater macular curvature changes from acute IOP elevation than highly myopic or emmetropic eyes, indicating increased sensitivity to pressure.

Tan Shayne S, Tun Tin A, Nongpiur Monisha E

Tan Royston K Y, Ng Gim Yew, Tun Tin A, Braeu Fabian A, Nongpiur Monisha E, Aung Tin et al.

Finite element analysis showed iris thickness, convexity, stiffness, and anterior chamber dimensions significantly influence angle narrowing during pupil dilation, guiding risk assessment for angle-closure glaucoma.

Tun Tin A, Atalay Eray, Liu Arthur, Liu Chang, Aung Tin, Nongpiur Monisha E

OCTA showed optic disc and macular microvasculature was significantly reduced only in primary angle closure glaucoma, not earlier stages, suggesting vascular changes correlate with glaucoma progression.

Tun Tin A, Nongpiur Monisha Esther, Xu Benjamin Y, Wang Xiaofei, Tan Marcus, Quah Joanne Hui Min et al.

This study found iridolenticular contact area (ILCA) is smaller in angle closure eyes and independently predicts angle closure, offering a novel biometric risk factor related to pupillary block.

Tan Shayne S, Tun Tin A, Aung Tin, Nongpiur Monisha E

This study found primary angle closure glaucoma eyes have higher initial IOP and narrower anterior segments than fellow eyes, suggesting these factors increase glaucoma risk after LPI.

Chuangsuwanich Thanadet, Tun Tin A, Braeu Fabian A, Wang Xiaofei, Chin Zhi Yun, Panda Satish K et al.

This study found normal-tension glaucoma patients experience greater optic nerve head strain from adduction than high-tension patients, suggesting gaze-induced stress may contribute to NTG progression.

Braeu Fabian A, Chuangsuwanich Thanadet, Tun Tin A, Perera Shamira, Husain Rahat, Thiery Alexandre H et al.

AI can predict optic nerve head robustness from a single OCT scan, potentially identifying glaucoma patients at higher risk for rapid vision loss, without needing invasive biomechanical testing.

Braeu Fabian A, Chuangsuwanich Thanadet, Tun Tin A, Perera Shamira A, Husain Rahat, Kadziauskiene Aiste et al.

This study found most 3D optic nerve head structural changes occur early in glaucoma in both neural and connective tissues, highlighting the need for early detection and monitoring for rapid visual field loss.

Chuangsuwanich Thanadet, Tun Tin A, Braeu Fabian A, Yeoh Clarice H Y, Chong Rachel S, Wang Xiaofei et al.

This study found highly myopic glaucoma and pathologic myopia with staphyloma cause greater optic nerve head strain from IOP elevation, indicating increased biomechanical vulnerability.

Tun Tin A, Sawicki Andrzej, Wilkos-Kuc Agnieszka, Aung Tin, Zarnowski Tomasz

This study found LPI-induced angle widening varies by angle closure mechanism, with thick peripheral irises showing less widening despite greater iris curvature reduction, guiding personalized treatment.

Thiéry Alexandre H, Braeu Fabian, Tun Tin A, Aung Tin, Girard Michaël J A

Geometric deep learning on OCT scans diagnosed glaucoma more accurately than CNNs or RNFL thickness, potentially simplifying and improving clinical diagnosis.

Braeu Fabian A, Thiéry Alexandre H, Tun Tin A, Kadziauskiene Aiste, Barbastathis George, Aung Tin et al.

Geometric deep learning accurately diagnosed glaucoma from 3D ONH OCT scans, identifying critical hourglass-pattern features in the neuroretinal rim, offering potential for improved clinical diagnosis and prognosis.

Chuangsuwanich Thanadet, Tun Tin A, Braeu Fabian A, Wang Xiaofei, Chin Zhi Yun, Panda Satish Kumar et al.

This study found higher optic nerve head strain from elevated pressure correlated with worse vision in high-tension glaucoma, but not normal-tension glaucoma, suggesting different disease mechanisms.

Porporato Natalia, Chong Rachel, Xu Benjamin Y, Tun Tin A, Quah Joanne HuiMin, Tan Marcus et al.

This study found extensive angle closure and shallow anterior chamber depth jointly predict higher intraocular pressure, especially in women with closed angles, indicating mechanical outflow obstruction.

Panda Satish K, Cheong Haris, Tun Tin A, Chuangsuwanich Thanadet, Kadziauskiene Aiste, Senthil Vijayalakshmi et al.

This study found that the 3D configuration of central retinal vessels, analyzed by AI, is a superior glaucoma diagnostic marker compared to standard RNFL thickness, potentially improving early detection.

Randhawa Jasmeen, Chiang Michael, Porporato Natalia, Pardeshi Anmol A, Dredge Justin, Apolo Aroca Galo et al.

An OCT deep learning classifier consistently detected angle closure across diverse populations, showing strong agreement with human examiners. This tool could aid ophthalmologists in assessing angle status.

Panda Satish K, Tan Royston K Y, Tun Tin A, Buist Martin L, Nongpiur Monisha, Baskaran Mani et al.

This study found irises in angle-closure glaucoma are stiffer and less permeable than healthy irises, suggesting biomechanical differences contribute to the disease and could inform future management.