Casale Ralph A

Wirostko Barbara M, Roy Chowdhury Uttio, Brandano Lisa A, Casale Ralph A, DeWalt Daniel J, Rykard Laura R et al.

QLS-111, a novel potassium channel opener, safely and effectively lowered eye pressure in animals, showing additive benefits with existing glaucoma drugs by reducing episcleral venous pressure, promising a new treatment.

Pervan-Steel Cynthia L, Roy Chowdhury Uttio, Sookdeo Hemchand K, Casale Ralph A, Dosa Peter I, Htoo Thurein M et al.

QLS-101, a novel prodrug, effectively lowered eye pressure in mice for 24 hours after daily topical application, converting to its active form in human eye tissues. This offers a new glaucoma treatment.