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Inhibition of histone deacetylases 1 and 3 protects injured retinal ganglion cells.
Chindasub Panida, Lindsey James D, Duong-Polk Karen, Leung Christopher K, Weinreb Robert N
Invest Ophthalmol Vis SciJan 20130 citationsBasic Science
MS-275, an HDAC1/3 inhibitor, protected retinal ganglion cells from death after optic nerve injury in mice, suggesting a potential neuroprotective glaucoma treatment.