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Eliott Dean

5 articles in GJC

5 articles in GJC

1.

Retinal Vasculopathy and Choroiditis after Pegcetacoplan Injection: Clinicopathologic Support for a Drug Hypersensitivity Reaction.

Nahar Ankur, Eliott Dean, Avery Robert L, Pulido Jose, Eagle Ralph C, Carrasco Jacqueline R et al.

Ophthalmol RetinaOct 20246 citationsCase Series

Studying enucleated eyes after pegcetacoplan, researchers found severe immune-mediated retinal vasculopathy and choroiditis, suggesting a delayed hypersensitivity reaction. This highlights a rare, serious drug complication.

2.

Chronic retinal necrosis: cytomegalovirus necrotizing retinitis associated with panretinal vasculopathy in non-HIV patients.

Schneider Eric W, Elner Susan G, van Kuijk Frederik J, Goldberg Naomi, Lieberman Ronni M, Eliott Dean et al.

RetinaOct 201365 citationsCase Series

This study characterized "chronic retinal necrosis" in non-HIV patients with limited immune dysfunction, finding CMV causes a mixed retinitis and severe panretinal vasculopathy, requiring prompt CMV-specific antiviral therapy to prevent neovascularization.

3.

Fluocinolone acetonide intravitreal implant for diabetic macular edema: a 3-year multicenter, randomized, controlled clinical trial.

Pearson P Andrew, Comstock Timothy L, Ip Michael, Callanan David, Morse Lawrence S, Ashton Paul et al.

OphthalmologyAug 2011160 citationsRandomized Controlled Trial

The FA implant for diabetic macular edema improved vision and reduced retinal thickening, but caused high rates of cataract and elevated intraocular pressure, requiring careful patient selection.

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