Varma Rohit

Rajagopalan Archeta, Pardeshi Anmol, Apolo Galo, Burkemper Bruce, Jiang Xuejuan, McKean-Cowdin Roberta et al.

AS-OCT angle width and iris area strongly predict IOP and ocular hypertension as angles narrow, unlike gonioscopy. This helps identify angle closure patients at higher risk for elevated IOP.

Richter Grace M, Xu Benjamin Y, Burkemper Bruce S, Jiang Xuejuan, Torres Mina, Choudhury Farzana et al.

This study found 4.8% OAG prevalence in Chinese Americans, with most cases undiagnosed and normal-tension. Key risk factors are age, IOP, axial length, family history, and diabetes, highlighting the need for screening.

Dhablania Nathan, Torres Mina, Burkemper Bruce, McKean-Cowdin Roberta, Jiang Xuejuan, Varma Rohit

This study found 22% of African Americans with eye disease were undiagnosed. Diabetes, infrequent eye exams, and trouble getting glasses were key predictors, highlighting the need for targeted screening to reduce vision loss.

Xu Benjamin Y, Richter Grace M, Burkemper Bruce S, Wang Dandan, Jiang Xuejuan, Torres Mina et al.

This study found primary angle closure glaucoma affects 1.1% of Chinese Americans, with most cases undiagnosed. Older age, family history, higher IOP, and shorter eyes increase risk, highlighting the need for early detection.

Varma Rohit, Jiang Xuejuan

Cho Austin, Lewinger Juan Pablo, Pardeshi Anmol A, Aroca Galo Apolo, Torres Mina, Nongpiur Monisha et al.

This study classified angle closure eyes using AS-OCT biometrics, finding that measurements, particularly in light, can distinguish disease severity and predict primary angle closure glaucoma, aiding risk stratification.

Zhou Sarah, Burkemper Bruce, Pardeshi Anmol A, Apolo Galo, Richter Grace, Jiang Xuejuan et al.

This study found myopia and longer axial length increase glaucoma risk similarly in Latino and Chinese Americans, but higher myopia prevalence in Chinese Americans narrows POAG prevalence differences, highlighting future impact of the myopia epidemic.

Zhou Sarah, Pardeshi Anmol A, Burkemper Bruce, Apolo Galo, Cho Austin, Jiang Xuejuan et al.

This study found primary angle closure disease risk rises sharply with hyperopia, not myopia. While anterior chamber depth is a stronger predictor, refractive error helps identify patients needing angle assessment.

Shan Jing, Pardeshi Anmol, Jiang Xuejuan, Richter Grace M, McKean-Cowdin Roberta, Varma Rohit et al.

This study found current AS-OCT imaging conventions misrepresent angle closure anatomy. A multi-image approach, starting at 25°-205°, better captures biometric means and ranges, improving diagnostic accuracy.

Grisafe Dominic J, McKean-Cowdin Roberta, Burkemper Bruce S, Xu Benjamin Y, Torres Mina, Varma Rohit

This study found visual field loss impacts quality of life differently by race/ethnicity, with Latinos/Chinese Americans reporting greater impact than Black Americans for similar loss, highlighting varied patient experiences.

Richter Grace M, Lee Jae Chang, Khan Nasir, Vorperian Alexander, Hand Brennan, Burkemper Bruce et al.

This study found that longer axial length, older age, male gender, and lower diastolic blood pressure are key determinants of macular vessel density in healthy African Americans, highlighting the need to consider these factors when interpreting OCTA.

Lifton Jacob, Burkemper Bruce, Jiang Xuejuan, Pardeshi Anmol A, Richter Grace, McKean-Cowdin Roberta et al.

This study found PACD eyes have attenuated angle widening from dark to light, linked to abnormal anterior chamber width changes, highlighting the need for dynamic angle assessment.

Shen Alice, Chiang Michael, Pardeshi Anmol A, McKean-Cowdin Roberta, Varma Rohit, Xu Benjamin Y

This study found deep learning misclassifications for angle closure from AS-OCT are explained by disagreement between anterior segment and angle parameters, potentially improving classifier performance and clarifying angle closure definitions.

Juliano Joseph, Burkemper Bruce, Lee Jae, Nelson Andrew, LeTran Vivian, Chu Zhongdi et al.

In glaucoma patients, higher IOP significantly reduced peripapillary vessel density, especially with longer axial length. This suggests impaired blood flow regulation in longer eyes, impacting glaucoma risk.

Grisafe Dominic J, Varma Rohit, Burkemper Bruce S, Xu Benjamin Y, Torres Mina, Fairbrother-Crisp Alicia et al.

This study found visual field loss significantly impacts African Americans' quality of life, especially driving ability and daily tasks, highlighting the burden of glaucoma on their functional independence.

Nousome Darryl, Mckean-Cowdin Roberta, Richter Grace M, Burkemper Bruce, Torres Mina, Varma Rohit et al.

This study found healthy Black Americans have thinner RNFLs than other ethnicities, even after adjusting for disc size, which is crucial for interpreting glaucoma tests.

Xu Benjamin Y, Lifton Jacob, Burkemper Bruce, Jiang Xuejuan, Pardeshi Anmol A, Moghimi Sasan et al.

In Chinese Americans, anterior chamber depth, lens vault, and iris curvature are the strongest biometric determinants of anterior chamber angle width, explaining sex-related differences and informing angle closure risk assessment.

Xu Benjamin Y, Chiang Michael, Chaudhary Shreyasi, Kulkarni Shraddha, Pardeshi Anmol A, Varma Rohit

Deep learning accurately detects angle closure and PACD from AS-OCT images, offering a promising automated tool to improve angle assessment and eye care access, especially in high-risk groups.

Chang Ryuna, Chu Zhongdi, Burkemper Bruce, Lee Gary C, Fard Ali, Durbin Mary K et al.

This study compared OCTA scan sizes (4.5x4.5mm vs. 6.0x6.0mm) for glaucoma diagnosis. Key finding: 4.5mm scans generally outperformed 6.0mm scans, especially in specific quadrants, suggesting higher resolution is better for detecting early changes.

Aref Ahmad A, Maleki Shervin, Tan Ou, Huang David, Varma Rohit, Shahidi Mahnaz

This study found glaucoma visual field loss is linked to reduced retinal oxygen delivery and increased oxygen extraction, suggesting oxygen deprivation contributes to glaucoma progression.

Zhang Xinbo, Parrish Richard K, Greenfield David S, Francis Brian A, Varma Rohit, Schuman Joel S et al.

This study found that baseline focal loss (OCT/VF) and thinner central corneal thickness predict faster glaucoma progression, aiding early identification of high-risk patients.

Varma Rohit, Jiang Xuejuan

Jiang Xuejuan, Torres Mina, Varma Rohit

This study found IOP variation, especially maximum IOP, independently predicts open-angle glaucoma risk, particularly in individuals with lower average IOPs, highlighting its importance beyond just mean IOP.

Zhang Xinbo, Dastiridou Anna, Francis Brian A, Tan Ou, Varma Rohit, Greenfield David S et al.

OCT detected glaucoma progression earlier and more often than visual fields, especially in early disease. GCC thinning remained a sensitive progression marker across all stages.

Varma Rohit, Jiang Xuejuan