Francis Brian A

Francis Brian A, Vera Vanessa, Kim Joshua, Basha Mahdi M, Lum Bryant, Grayson Douglas et al.

Ab-externo gel stent implantation effectively reduced intraocular pressure (34%) and medication burden (61%) in glaucoma patients, with transient hypotony (28%) as the main adverse event, expanding surgical options.

Nassiri Nariman, Tseng Victoria L, Kim Chaesik, Dentone Peter, Francis Nathan M, Chopra Alexander L et al.

MP-TLT effectively lowered IOP and medication use in advanced glaucoma patients with prior tube shunts, offering a safe option for managing uncontrolled pressure.

Francis Brian A, Dentone Peter, Heilweil Gad, Chopra Vikas, Nassiri Nariman

Ophthalmic endoscopy effectively visualized diverse causes of atypical uveitis-glaucoma-hyphema syndrome, including haptic issues and vascular lesions, enabling precise surgical management for these complex cases.

Dastiridou Anna, Kassos Ioannis, Katsanos Andreas, Diafas Asterios, Androudi Sofia, Chopra Vikas et al.

This study found the ISNT rule, useful for nerve fiber layer thickness, does not reliably apply to radial peripapillary capillary vessel density in healthy eyes, impacting glaucoma assessment.

Swamy Ramya, Francis Brian A, Akil Handan, Yelenskiy Aleksandr, Francis Brandon A, Chopra Vikas et al.

Trabectome AIT effectively lowered IOP in uveitic glaucoma patients, offering a safe option to reduce pressure and medication, with high 12-month success, avoiding more invasive surgeries.

Zhang Xinbo, Parrish Richard K, Greenfield David S, Francis Brian A, Varma Rohit, Schuman Joel S et al.

This study found that baseline focal loss (OCT/VF) and thinner central corneal thickness predict faster glaucoma progression, aiding early identification of high-risk patients.

Akil Handan, Vu Priscilla Q, Nguyen Anhtuan H, Nugent Alexander, Chopra Vikas, Francis Brian A et al.

A venting stitch for valveless glaucoma shunts was studied, finding it safely and effectively controls early post-operative IOP, reducing hypotony risk and medication needs.

Huang Alex S, Francis Brian A, Weinreb Robert N

This review highlights advanced imaging techniques that reveal aqueous humor outflow structure and function, crucial for developing better glaucoma treatments by understanding outflow pathways.

Zhang Xinbo, Dastiridou Anna, Francis Brian A, Tan Ou, Varma Rohit, Greenfield David S et al.

OCT detected glaucoma progression earlier and more often than visual fields, especially in early disease. GCC thinning remained a sensitive progression marker across all stages.

Francis Brian A, Fernandes Rodrigo A B, Akil Handan, Chopra Vikas, Diniz Bruno, Tan James et al.

Implanting a second glaucoma drainage device effectively lowered IOP below 21 mmHg for up to three years, often requiring continued medication. This offers a viable option for refractory glaucoma management.

Srinivas Sowmya, Dastiridou Anna, Durbin Mary K, Nittala Muneeswar G, Huang Alex A, Tan James C H et al.

This study found glaucoma patients have significantly lower lamina cribrosa intensity than glaucoma suspects, suggesting this measurement could be a novel glaucoma indicator.

Zhang Xinbo, Dastiridou Anna, Francis Brian A, Tan Ou, Varma Rohit, Greenfield David S et al.

This study found that baseline focal GCC and NFL loss on FDOCT are the strongest predictors of visual field progression in glaucoma, helping identify patients at higher risk.

Huang Alex S, Saraswathy Sindhu, Dastiridou Anna, Begian Alan, Mohindroo Chirayu, Tan James C H et al.

In human enucleated eyes, trabecular bypass stents placed in areas initially lacking aqueous outflow significantly improved outflow as shown by angiography, suggesting targeted glaucoma treatment potential.

Richter Grace M, Zhang Xinbo, Tan Ou, Francis Brian A, Chopra Vikas, Greenfield David S et al.

OCT disc variables were studied for glaucoma diagnosis. Adjusting for disc size/axial length did not improve accuracy; however, rim area and vertical CDR showed high diagnostic value.

Dang Yalong, Kaplowitz Kevin, Parikh Hardik A, Roy Pritha, Loewen Ralitsa T, Francis Brian A et al.

Trabectome surgery effectively lowered intraocular pressure in steroid-induced glaucoma patients, achieving greater IOP reduction than in POAG, making it a viable treatment option.

Akil Handan, Chopra Vikas, Huang Alex, Loewen Nils, Noguchi Jonathan, Francis Brian A

Trabectome surgery showed similar positive outcomes for both pigmentary and primary open-angle glaucoma patients, indicating its effectiveness across these glaucoma types.

Francis Brian A, Pouw Andrew, Jenkins Dennis, Babic Kelly, Vakili Ghazal, Tan James et al.

Lens extraction and endoscopic cycloplasty for severe plateau iris syndrome significantly opened the angle and shrunk ciliary processes, reversing the anatomical cause of angle closure.

Tan James C H, Francis Brian A, Noecker Robert, Uram Martin, Dustin Laurie, Chopra Vikas

ECP-plus effectively lowered IOP and medication burden in refractory glaucoma patients, offering a viable treatment option with acceptable complication rates for difficult cases.

Marion Kenneth M, Maram Jyotsna, Pan Xiaojing, Dastiridou Anna, Zhang ZhouYuan, Ho Alex et al.

This study found two different SD-OCT devices provide comparable and highly reproducible anterior chamber angle measurements, suggesting they are interchangeable for clinical glaucoma assessment.

Loewen Nils A, Zhang Xinbo, Tan Ou, Francis Brian A, Greenfield David S, Schuman Joel S et al.

Combining FD-OCT measurements (NFL, GCC, disc) into a Glaucoma Structural Diagnostic Index (GSDI) significantly improved glaucoma diagnostic accuracy, especially for advanced disease, offering better clinical detection.

Hwang Jeremy C, Khine Kay T, Lee Jennifer C, Boyer David S, Francis Brian A

MSM dietary supplement was linked to acute angle closure via ciliary body edema. This highlights MSM's potential to cause glaucoma, similar to other sulfa drugs, requiring consumer warnings.

Le Phuc V, Zhang Xinbo, Francis Brian A, Varma Rohit, Greenfield David S, Schuman Joel S et al.

This study found advanced glaucoma imaging technologies show minimal site-to-site variation compared to glaucoma changes, supporting data pooling across centers for better research.

Cowan Lisa A, Khine Kay T, Chopra Vikas, Fazio Doreen T, Francis Brian A

Nd:YAG vitreolysis for floaters can cause refractory open-angle glaucoma, appearing weeks to months later. This complication may require chronic medical or surgical management.

Francis Brian A, Kwon Julie, Fellman Ronald, Noecker Robert, Samuelson Thomas, Uram Martin et al.

This review covers anterior segment endoscopy, detailing ECP's use, technique, and patient selection, comparing it to TCP, and highlighting other endoscope-assisted surgical applications.

Sehi Mitra, Goharian Iman, Konduru Ranjith, Tan Ou, Srinivas Sowmya, Sadda Srinivas R et al.

This study found that glaucomatous eyes with single-hemifield damage have reduced retinal blood flow, correlating with structural loss in the affected and seemingly normal hemispheres, highlighting blood flow's role in glaucoma progression.