Gao Kai

Xiong Jian, Li Fei, Song Diping, Tang Guangxian, He Junjun, Gao Kai et al.

FusionNet, an AI combining visual fields and OCT scans, detected glaucoma better than single-modality AI and specialists, highlighting multimodal AI's clinical value for diagnosis.

Li Fei, Lin Fengbin, Gao Kai, Cheng Weijing, Song Yunhe, Liu Yuhong et al.

This study found enlarged foveal avascular zone (FAZ) area on OCTA predicts structural glaucoma progression (RNFL/GC-IPL thinning), but not visual field decline, offering a potential early biomarker.

Lin Fengbin, Li Fei, Gao Kai, He Wanbing, Zeng Jun, Chen Yu et al.

This study found that deep macular vessel density (DCP VD) decreased significantly faster in glaucoma patients with high myopia, especially with lower baseline VD, suggesting increased microvascular vulnerability.

Gao Kai, Song Shaozhen, Johnstone Murray A, Zhang Qinqin, Xu Jingjiang, Zhang Xiulan et al.

PhS-OCT showed glaucoma eyes have reduced pulsatile trabecular meshwork motion, suggesting altered tissue stiffness. This measure could help characterize outflow pathway abnormalities in glaucoma.

Zhou Rouxi, Li Fei, Gao Kai, Zhang Xiulan

This study found smaller anterior chamber volume (ACV) predicts higher IOP elevation risk after LPI in primary angle closure disease, making ACV a useful clinical predictor.

Chen Shida, Liu Yaoming, Li Fei, Gao Kai, Zhou Rouxi, Zhang Xiulan

This study found LPI causes unified iris bow reduction across all clock positions, with 4-position measurements reliably reflecting 12-position. About one-third of eyes retained iris bowing after LPI.

Li Fei, Zhou Rouxi, Gao Kai, Jin Ling, Zhang Xiulan

This SS-OCT study found anterior chamber volume (ACV) accurately differentiates narrow from open angles. For narrow angles, a model combining iris volume, iris thickness, and angle open distance helps classify closure types, aiding clinical management.

Huang Wenbin, Li Xingyi, Gao Kai, Zhang Xiulan

Subconjunctival dexamethasone for acute angle closure accelerated IOP reduction and improved treatment success within 24 hours, suggesting it's a beneficial adjunct therapy.

Liu Yaoming, Chen Yang, Wang Yayi, Zhang Xinyu, Gao Kai, Chen Shida et al.

This study found distinct microRNA profiles in glaucoma patients' aqueous humor, with specific miRNAs differing based on disease severity, suggesting new targets for glaucoma pathogenesis and treatment.

Gao Kai, Li Fei, Li Yingqi, Li Xingyi, Huang Wenbin, Chen Shida et al.

This study found primary open-angle and angle-closure glaucoma eyes have a thicker anterior choroid than healthy eyes, suggesting its role in glaucoma pathogenesis.

Gao Kai, Li Fei, Aung Tin, Zhang Xiulan

This study found Schlemm's Canal (SC) changes negatively correlated with IOP fluctuations only in the inferior quadrant of healthy eyes. SC imaging could help understand IOP changes and glaucoma.

Li Fei, Gao Kai, Li Xingyi, Chen Shida, Huang Wenbin, Zhang Xiulan

Valsalva maneuver thickens the anterior choroid and ciliary body, narrowing the anterior chamber, but doesn't affect the posterior choroid. This suggests anterior choroidal involvement in IOP elevation and angle closure.