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Quantitative Microstructural Analysis of Cellular and Tissue Remodeling in Human Glaucoma Optic Nerve Head.
Guan Carolyn, Pease Mary Ellen, Quillen Sarah, Ling Yik Tung Tracy, Li Ximin, Kimball Elizabeth et al.
Invest Ophthalmol Vis SciOct 202217 citationsBasic Science
Glaucoma significantly alters the optic nerve head, showing astrocyte migration into axonal bundles, changes in astrocyte structure, increased basement membrane, and thinning of connective tissue beams, contributing to nerve damage.