Heegaard Steffen

Nissen Kristoffer, Christensen Jane, Hindso Tine Gadegaard, Faber Carsten, Bagger Mette, Heegaard Steffen et al.

Danish iris melanoma incidence increased significantly, driven by sun-exposed inferior tumors, suggesting ultraviolet radiation plays a pathogenic role in its development.

Christiansen Jacob, Mathiasen René, Heegaard Steffen, Kjeldsen Sia, Schmiegelow Kjeld, Siersma Volkert et al.

This study found over half of children with brain tumors had pre-diagnosis eye signs, associated with longer diagnostic intervals and increased mortality, highlighting critical ophthalmological assessment for earlier diagnosis.

Utheim Tor Paaske, Chen Xiangjun, Fineide Fredrik, Steinkjer Tore, Heegaard Steffen, Kolko Miriam et al.

A short dexamethasone regimen improved dry eye symptoms and signs, especially in those with more severe baseline disease, suggesting severity predicts better response.

Fineide Fredrik, Magnø Morten, Dahlø Kristian, Kolko Miriam, Heegaard Steffen, Vehof Jelle et al.

Topical glaucoma medications, especially preserved ones, negatively impact meibomian glands, causing dry eye and reduced gland function. This affects patient quality of life and treatment adherence.

Bentin Josephine Mejdahl, Heegaard Steffen, Jørgensen Niklas Rye, Grahnemo Louise, Hamann Steffen

This review highlights optic disc drusen's calcified nature as a potential treatment target, suggesting therapies focused on calcification might prevent vision loss from these common, yet sometimes severe, optic nerve anomalies.

Nissen Kristoffer, Skibsted Simon Persson, Bagger Mette Marie, Ejstrup Rasmus, Faber Carsten, Riise Per et al.

Combined cataract surgery and iris prosthesis after iridocyclectomy safely alleviates photic symptoms in most patients. However, it carries increased complication risks, especially with prior brachytherapy, highlighting the need for careful patient selection.

Thein Anna-Sophie, Hedengran Anne, Azuara-Blanco Augusto, Arita Reiko, Cvenkel Barbara, Gazzard Gus et al.

Experts defined key outcomes (e.g., ocular surface, dryness, quality of life) for consistently assessing glaucoma eye drop side effects in clinical trials, improving future research comparability and patient safety.

Hedengran Anne, Freiberg Josefine Clement, Hansen Pernille May, Jacobsen Jette, Larsen Susan Weng, Harloff-Helleberg Stine et al.

Generic BAK-preserved travoprost caused more goblet cell loss than branded PQ-preserved travoprost, suggesting PQ preservation is preferable for glaucoma treatment and generics aren't identical.

Correll Mette Hedegaard, Crouzet Emmanuel, Gain Philippe, He Zhiguo, Udsen Maja Søberg, Kiilgaard Jens Folke et al.

Intracameral EdU injection effectively labeled proliferating rabbit corneal endothelial cells, which migrated centripetally from the periphery. This method can help identify progenitor cells for corneal endothelial dysfunction therapies.

Sørensen Nina Buus, Christiansen Anders Tolstrup, Kjaer Troels Wesenberg, Klemp Kristian, Cour Morten la, Heegaard Steffen et al.

This porcine RRD model, mimicking retinal tension loss, showed permanent retinal function decrease and ganglion cell death within two weeks, offering a platform for new treatment research.

Skougaard Marie, Heegaard Steffen, Malmqvist Lasse, Hamann Steffen

Studying 1713 enucleated eyes, optic disc drusen (ODD) prevalence was 1.8%. Large, deep ODD were linked to thickened nerve fiber layers and pseudopapilledema, suggesting axonal crowding. This highlights ODD's impact on optic nerve structure.

Tiedemann Daniel, Mouhammad Zaynab A, Utheim Tor P, Dartt Darlene A, Heegaard Steffen, Petrovski Goran et al.

Glaucoma eye drops, especially preserved ones, harm conjunctival goblet cells, impacting ocular surface health. Prostaglandin analogs spare them, and goblet cell density may predict surgical outcomes.

Jacobsen Mads Forslund, Thomsen Ann Sofia Skou, Bach-Holm Daniella, Doroudian Ghazaleh, Nissen Kamilla Rothe, Fugleholm Kåre et al.

This study found craniopharyngioma surgery offers slight visual acuity improvement, especially with papilledema or early intervention. Early ophthalmological assessment is crucial for detection and better outcomes.

Obara Elisabeth Anne, Hannibal Jens, Heegaard Steffen, Fahrenkrug Jan

This study found that diabetic retinopathy significantly reduces melanopsin-expressing retinal ganglion cells, potentially explaining circadian rhythm disruptions like sleep disorders seen in these patients.

Obara Elisabeth Anne, Hannibal Jens, Heegaard Steffen, Fahrenkrug Jan

This study found significant loss of melanopsin-expressing retinal ganglion cells in severely staged human glaucoma, but not mild cases. This suggests mRGC integrity could help assess glaucoma progression.

Kessing Svend V, Heegaard Steffen, Nissen Ole I

This study evaluated a new clear-cornea glaucoma procedure (IDK) for refractory cases, finding it achieved excellent, stable IOP control (around 10 mmHg) with favorable, non-cystic blebs, suggesting a promising surgical option.

Lindegaard Jens, Isager Peter, Prause Jan Ulrik, Heegaard Steffen

This study found optic nerve invasion in 5.7% of uveal melanomas, with postlaminar invasion linked to worse survival. Clinicians should suspect invasion with juxtapapillary tumors, vision loss, or increased IOP.

Hannibal Jens, Hindersson Peter, Ostergaard Jens, Georg Birgitte, Heegaard Steffen, Larsen Philip Just et al.

This study found melanopsin in human RGCs co-localized with PACAP, forming the RHT and persisting in blind eyes. This suggests melanopsin is crucial for non-visual light perception and circadian rhythms in both sighted and blind individuals.