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MiR-29b Downregulation by p53/Sp1 Complex Plays a Critical Role in Bleb Scar Formation After Glaucoma Filtration Surgery.
Li Ning, Wang Zixi, Yang Fan, Hu Wenjun, Zha Xiaojun, Duan Xuanchu
Transl Vis Sci TechnolDec 20236 citationsBasic Science
This study found that the p53/Sp1 complex downregulates miR-29b, promoting bleb scarring after glaucoma surgery. Targeting this pathway could prevent surgical failure.