Iglesias Adriana I

Quint Wim H, Tadema Kirke C D, Crins Johan H C, Kokke Nina C C J, Meester-Smoor Magda A, Willemsen Rob et al.

This study developed a zebrafish screening pipeline to assess ocular health. It successfully identified disease-like changes in mutant fish, validating zebrafish as a promising model for gene screening in human eye diseases.

Iglesias Adriana I, Ong Jue Sheng, Khawaja Anthony P, Gharahkhani Puya, Tedja Milly S, Verhoeven Virginie J M et al.

This study found no significant genetic overlap between myopia and primary open-angle glaucoma, suggesting their co-occurrence isn't due to shared common gene variants, except for optic disc size.

Laville Vincent, Kang Jae H, Cousins Clara C, Iglesias Adriana I, Nagy Réka, Cooke Bailey Jessica N et al.

This study found limited genetic correlation between diabetes and glaucoma traits, suggesting these common conditions have largely distinct genetic underpinnings, which may impact future research and treatment strategies.

Ghanbari Mohsen, Iglesias Adriana I, Springelkamp Henriët, van Duijn Cornelia M, Ikram M Arfan, Dehghan Abbas et al.

This study found specific genetic variants in microRNAs and their binding sites are linked to glaucoma traits, suggesting these miRNAs and their target genes are potential therapeutic targets for POAG.

Nag Abhishek, Lu Han, Arno Matthew, Iglesias Adriana I, Bonnemaijer Pieter, Broer Linda et al.

This study found the common Gln368Stop MYOC mutation has much lower penetrance for glaucoma/high IOP than previously thought, reducing its utility as a glaucoma screening tool.