Jayasundera Thiran

Pennesi Mark Edward, Yang Paul, Birch David G, Weng Christina Y, Moore Anthony T, Iannaccone Alessandro et al.

This gene therapy for X-linked retinoschisis was generally safe but showed no measurable clinical benefit in vision, visual fields, or retinal structure, indicating limited efficacy for patients.

Birch David G, Bernstein Paul S, Iannacone Alessandro, Pennesi Mark E, Lam Byron L, Heckenlively John et al.

Oral valproic acid for autosomal dominant retinitis pigmentosa was studied. Key finding: VPA did not improve vision; the VPA group had worse visual field outcomes than placebo. Clinical relevance: VPA is not supported for ADRP treatment.

Abalem Maria Fernanda, Otte Benjamin, Andrews Chris, Joltikov Katherine A, Branham Kari, Fahim Abigail T et al.

This study found that wider Stargardt disease extent on UWF-FAF correlates with more constricted peripheral vision, worse central vision, and retinal dysfunction, aiding in functional prognosis.

Fahim Abigail T, Khan Naheed W, Zahid Sarwar, Schachar Ira H, Branham Kari, Kohl Susanne et al.

Achromatopsia patients show age-dependent FAF patterns; foveal hyperfluorescence is an early diagnostic sign, progressing to hypofluorescence with atrophy, aiding early diagnosis and tracking disease progression.

Danesh-Meyer Helen V, Ku Judy Y F, Papchenko Taras L, Jayasundera Thiran, Hsiang John C, Gamble Greg D

This study found clinical disc damage (DDLS) strongly correlates with visual field loss, especially in superior/inferior regions, suggesting DDLS is a useful, accessible tool for assessing glaucoma severity.

Jayasundera Thiran, Danesh-Meyer Helen V, Donaldson Mark, Gamble Greg

This study found poor agreement among different methods (stereo photos, HRT, DISCAM, ophthalmoscopy) for estimating VCDR, especially in small discs/cups. Clinically, these methods are not interchangeable for VCDR assessment.