Jin Rui

2 articles in GJC

Secreted protein acidic and rich in cysteine (SPARC)-null mice exhibit more uniform outflow.

Swaminathan Swarup S, Oh Dong-Jin, Kang Min Hyung, Ren Ruiyi, Jin Rui, Gong Haiyan et al.

Invest Ophthalmol Vis SciMar 201380 citationsBasic Science

SPARC-null mice showed more uniform aqueous outflow and lower IOP due to altered trabecular meshwork collagen. This suggests SPARC modulates outflow, offering a potential target for glaucoma therapy.

Full abstract PubMed

Thrombospondin-1 (TSP1)-null and TSP2-null mice exhibit lower intraocular pressures.

Haddadin Ramez I, Oh Dong-Jin, Kang Min Hyung, Villarreal Guadalupe, Kang Ja-Heon, Jin Rui et al.

Invest Ophthalmol Vis SciSep 201253 citationsBasic Science

Studying TSP1/TSP2-null mice, researchers found these proteins regulate IOP. Their absence led to lower IOP, suggesting TSP1/TSP2 inhibition could be a novel glaucoma treatment target.

Full abstract PubMed

All 2 articles loaded

Global Search

Jin Rui

Secreted protein acidic and rich in cysteine (SPARC)-null mice exhibit more uniform outflow.

Thrombospondin-1 (TSP1)-null and TSP2-null mice exhibit lower intraocular pressures.