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Matrix metalloproteinases and their inhibitors in aqueous humor of patients with pseudoexfoliation syndrome/glaucoma and primary open-angle glaucoma.
Schlötzer-Schrehardt Ursula, Lommatzsch Jürgen, Küchle Michael, Konstas Anastasios G P, Naumann Gottfried O H
Invest Ophthalmol Vis SciMar 2003178 citationsObservational Study
This study found imbalanced MMP-TIMP ratios and reduced active MMP-2 in aqueous humor of PEX and POAG patients. This imbalance may cause abnormal matrix accumulation, contributing to glaucoma pathogenesis.