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Konstantakopoulou Evgenia

18 articles in GJC

18 articles in GJC

2.

Selective Laser Trabeculoplasty After Medical Treatment for Glaucoma or Ocular Hypertension.

Konstantakopoulou Evgenia, Gazzard Gus, Garway-Heath David, Adeleke Mariam, Ambler Gareth, Vickerstaff Victoria et al.

JAMA OphthalmolApr 20255 citationsRandomized Controlled Trial

Secondary SLT after 3+ years of drops reduced medication for stable glaucoma/OHT patients and lowered IOP for uncontrolled eyes, but didn't eliminate surgery. This supports SLT as a valuable secondary treatment option.

3.

The Impact of Baseline Intraocular Pressure on Initial Treatment Response in the LiGHT Trial: Selective Laser Trabeculoplasty versus Medication.

Fahy Eamonn T, Montesano Giovanni, Garg Anurag, Vickerstaff Victoria, Konstantakopoulou Evgenia, Gazzard Gus

OphthalmologyJul 202415 citationsRandomized Controlled Trial

This study found that SLT achieved greater IOP lowering than medication at higher baseline pressures, while medication performed better at lower baseline pressures, guiding initial treatment choice.

7.

Laser in Glaucoma and Ocular Hypertension (LiGHT) Trial: Six-Year Results of Primary Selective Laser Trabeculoplasty versus Eye Drops for the Treatment of Glaucoma and Ocular Hypertension.

Gazzard Gus, Konstantakopoulou Evgenia, Garway-Heath David, Adeleke Mariam, Vickerstaff Victoria, Ambler Gareth et al.

OphthalmologySep 2022156 citationsRandomized Controlled Trial

The LiGHT trial showed primary SLT offers better long-term glaucoma control than drops, reducing progression and need for incisional and cataract surgeries over six years, making it a safe, effective first-line option.

12.

Visual Field Outcomes from the Multicenter, Randomized Controlled Laser in Glaucoma and Ocular Hypertension Trial (LiGHT).

Wright David M, Konstantakopoulou Evgenia, Montesano Giovanni, Nathwani Neil, Garg Anurag, Garway-Heath David et al.

OphthalmologyApr 202056 citationsRandomized Controlled Trial

This study found that initial selective laser trabeculoplasty (SLT) led to less visual field progression in glaucoma/ocular hypertension patients compared to initial medical therapy, suggesting SLT may be a better first-line option.

13.

Efficacy of Repeat Selective Laser Trabeculoplasty in Medication-Naive Open-Angle Glaucoma and Ocular Hypertension during the LiGHT Trial.

Garg Anurag, Vickerstaff Victoria, Nathwani Neil, Garway-Heath David, Konstantakopoulou Evgenia, Ambler Gareth et al.

OphthalmologyOct 201946 citationsRandomized Controlled Trial

Repeat SLT in medication-naive glaucoma/OHT patients effectively maintains IOP control for at least 18 months, with similar duration of effect to initial treatment, offering a valuable retreatment option.

14.

Primary Selective Laser Trabeculoplasty for Open-Angle Glaucoma and Ocular Hypertension: Clinical Outcomes, Predictors of Success, and Safety from the Laser in Glaucoma and Ocular Hypertension Trial.

Garg Anurag, Vickerstaff Victoria, Nathwani Neil, Garway-Heath David, Konstantakopoulou Evgenia, Ambler Gareth et al.

OphthalmologyApr 20190 citationsRandomized Controlled Trial

Primary SLT for OAG/OHT showed comparable early IOP lowering to medication, achieving drop-free disease control in ~75% of eyes at 36 months, supporting its effectiveness and safety.

15.

Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial.

Gazzard Gus, Konstantakopoulou Evgenia, Garway-Heath David, Garg Anurag, Vickerstaff Victoria, Hunter Rachael et al.

LancetMar 20190 citationsRandomized Controlled Trial

This study found SLT is as effective as eye drops for first-line glaucoma/ocular hypertension treatment, with 74% needing no drops at 3 years and being more cost-effective, supporting its routine use.

16.

Clinical effectiveness of the Manchester Glaucoma Enhanced Referral Scheme.

Gunn Patrick J G, Marks Joanne R, Konstantakopoulou Evgenia, Edgar David F, Lawrenson John G, Roberts Stephen A et al.

Br J OphthalmolOct 20180 citationsObservational Study

This study found the Manchester Glaucoma Enhanced Referral Scheme effectively filters patients, demonstrating low false-positive (15.5%) and false-negative (0.8%) rates. This suggests efficient resource allocation and minimizes missed glaucoma cases.

17.

The Laser in Glaucoma and Ocular Hypertension (LiGHT) trial. A multicentre randomised controlled trial: baseline patient characteristics.

Konstantakopoulou Evgenia, Gazzard Gus, Vickerstaff Victoria, Jiang Yuzhen, Nathwani Neil, Hunter Rachael et al.

Br J OphthalmolOct 201721 citationsRandomized Controlled Trial

The LiGHT trial compared initial SLT versus medication for glaucoma/OHT, finding baseline patient characteristics were consistent with other studies, paving the way for crucial real-world treatment efficacy and cost-effectiveness comparisons.

18.

Laser in Glaucoma and Ocular Hypertension (LiGHT) trial. A multicentre, randomised controlled trial: design and methodology.

Gazzard Gus, Konstantakopoulou Evgenia, Garway-Heath David, Barton Keith, Wormald Richard, Morris Stephen et al.

Br J OphthalmolSep 201760 citationsRandomized Controlled Trial

The LiGHT trial is studying if initial selective laser trabeculoplasty (SLT) is better than eye drops for primary open-angle glaucoma/ocular hypertension, focusing on quality of life and cost-effectiveness.

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