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Nathwani Neil

๐Ÿ‡ฆ๐Ÿ‡ก Moorfields Eye Hospital NHS Foundation Trust
ORCIDOpenAlex17 articles in GJC

17 articles in GJC

3.

Selective Laser Trabeculoplasty After Medical Treatment for Glaucoma or Ocular Hypertension.

Konstantakopoulou Evgenia, Gazzard Gus, Garway-Heath David, Adeleke Mariam, Ambler Gareth, Vickerstaff Victoria et al.

JAMA OphthalmolApr 20255 citationsRandomized Controlled Trial

Secondary SLT after 3+ years of drops reduced medication for stable glaucoma/OHT patients and lowered IOP for uncontrolled eyes, but didn't eliminate surgery. This supports SLT as a valuable secondary treatment option.

7.

Laser in Glaucoma and Ocular Hypertension (LiGHT) Trial: Six-Year Results of Primary Selective Laser Trabeculoplasty versus Eye Drops for the Treatment of Glaucoma and Ocular Hypertension.

Gazzard Gus, Konstantakopoulou Evgenia, Garway-Heath David, Adeleke Mariam, Vickerstaff Victoria, Ambler Gareth et al.

OphthalmologySep 2022156 citationsRandomized Controlled Trial

The LiGHT trial showed primary SLT offers better long-term glaucoma control than drops, reducing progression and need for incisional and cataract surgeries over six years, making it a safe, effective first-line option.

10.

Laser in Glaucoma and Ocular Hypertension Trial (LIGHT) in China - A Randomized Controlled Trial: Design and Baseline Characteristics.

Yang Yangfan, Jiang Yuzhen, Huang Shitong, Zhang Xinyi, Nathwani Neil, Lin Mingkai et al.

Am J OphthalmolMay 202110 citationsRandomized Controlled Trial

This trial compared SLT versus medication as first-line glaucoma treatment in China. Baseline data showed younger, more myopic patients with worse visual fields than a similar UK study, highlighting population differences in glaucoma presentation.

11.

Visual Field Outcomes from the Multicenter, Randomized Controlled Laser in Glaucoma and Ocular Hypertension Trial (LiGHT).

Wright David M, Konstantakopoulou Evgenia, Montesano Giovanni, Nathwani Neil, Garg Anurag, Garway-Heath David et al.

OphthalmologyApr 202056 citationsRandomized Controlled Trial

This study found that initial selective laser trabeculoplasty (SLT) led to less visual field progression in glaucoma/ocular hypertension patients compared to initial medical therapy, suggesting SLT may be a better first-line option.

12.

Efficacy of Repeat Selective Laser Trabeculoplasty in Medication-Naive Open-Angle Glaucoma and Ocular Hypertension during the LiGHT Trial.

Garg Anurag, Vickerstaff Victoria, Nathwani Neil, Garway-Heath David, Konstantakopoulou Evgenia, Ambler Gareth et al.

OphthalmologyOct 201946 citationsRandomized Controlled Trial

Repeat SLT in medication-naive glaucoma/OHT patients effectively maintains IOP control for at least 18 months, with similar duration of effect to initial treatment, offering a valuable retreatment option.

13.

Primary Selective Laser Trabeculoplasty for Open-Angle Glaucoma and Ocular Hypertension: Clinical Outcomes, Predictors of Success, and Safety from the Laser in Glaucoma and Ocular Hypertension Trial.

Garg Anurag, Vickerstaff Victoria, Nathwani Neil, Garway-Heath David, Konstantakopoulou Evgenia, Ambler Gareth et al.

OphthalmologyApr 20190 citationsRandomized Controlled Trial

Primary SLT for OAG/OHT showed comparable early IOP lowering to medication, achieving drop-free disease control in ~75% of eyes at 36 months, supporting its effectiveness and safety.

14.

Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial.

Gazzard Gus, Konstantakopoulou Evgenia, Garway-Heath David, Garg Anurag, Vickerstaff Victoria, Hunter Rachael et al.

LancetMar 20190 citationsRandomized Controlled Trial

This study found SLT is as effective as eye drops for first-line glaucoma/ocular hypertension treatment, with 74% needing no drops at 3 years and being more cost-effective, supporting its routine use.

15.

The Laser in Glaucoma and Ocular Hypertension (LiGHT) trial. A multicentre randomised controlled trial: baseline patient characteristics.

Konstantakopoulou Evgenia, Gazzard Gus, Vickerstaff Victoria, Jiang Yuzhen, Nathwani Neil, Hunter Rachael et al.

Br J OphthalmolOct 201721 citationsRandomized Controlled Trial

The LiGHT trial compared initial SLT versus medication for glaucoma/OHT, finding baseline patient characteristics were consistent with other studies, paving the way for crucial real-world treatment efficacy and cost-effectiveness comparisons.

16.

Patients With Normal Tension Glaucoma Have Relative Sparing of the Relative Afferent Pupillary Defect Compared to Those With Open Angle Glaucoma and Elevated Intraocular Pressure.

Lawlor Mitchell, Quartilho Ana, Bunce Catey, Nathwani Neil, Dowse Emily, Kamal Debbie et al.

Invest Ophthalmol Vis SciOct 20179 citationsCross-Sectional Study

Normal tension glaucoma patients show less relative afferent pupillary defect for a given visual field loss than high-pressure glaucoma patients, suggesting differing damage mechanisms and potentially mitochondrial involvement in NTG.

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