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Konstas A G P

15 articles in GJC

15 articles in GJC

2.

Twenty-four hour efficacy with the dorzolamide/timolol-fixed combination compared with the brimonidine/timolol-fixed combination in primary open-angle glaucoma.

Konstas A G P, Quaranta L, Yan D B, Mikropoulos D G, Riva I, Gill N K et al.

Eye (Lond)Jan 201217 citationsRandomized Controlled Trial

This study compared two glaucoma fixed combinations, finding dorzolamide/timolol provided superior 24-hour IOP reduction compared to brimonidine/timolol in primary open-angle glaucoma, offering better pressure control.

3.

24-h Intraocular pressure control with evening-dosed travoprost/timolol, compared with latanoprost/timolol, fixed combinations in exfoliative glaucoma.

Konstas A G P, Mikropoulos D G, Embeslidis T A, Dimopoulos A T, Papanastasiou A, Haidich A-B et al.

Eye (Lond)Oct 201021 citationsRandomized Controlled Trial

This study found travoprost/timolol fixed combination provided superior 24-hour IOP control, including lower mean and peak pressures, compared to latanoprost/timolol in exfoliative glaucoma, offering a potentially more effective treatment option.

4.

Untreated 24-h intraocular pressures measured with Goldmann applanation tonometry vs nighttime supine pressures with Perkins applanation tonometry.

Quaranta L, Konstas A G P, Rossetti L, Garcia-Feijoo J, O'Brien C, Nasr M B et al.

Eye (Lond)Jul 201025 citationsCohort Study

This study found untreated nighttime supine IOPs (Perkins) were not significantly higher than daytime sitting IOPs (Goldmann), but daytime readings don't consistently predict highest nighttime pressures, highlighting potential missed peaks.

5.

Twenty-four-hour intraocular pressure control with the travoprost/timolol maleate fixed combination compared with travoprost when both are dosed in the evening in primary open-angle glaucoma.

Konstas A G P, Mikropoulos D, Haidich A-B, Ntampos K S, Stewart W C

Br J OphthalmolApr 200930 citationsRandomized Controlled Trial

This study found travoprost/timolol fixed combination significantly lowered 24-hour intraocular pressure and fluctuation more than travoprost alone in glaucoma patients, offering superior IOP control.

7.

Second-line therapy with dorzolamide/timolol or latanoprost/timolol fixed combination versus adding dorzolamide/timolol fixed combination to latanoprost monotherapy.

Konstas A G P, Mikropoulos D, Dimopoulos A T, Moumtzis G, Nelson L A, Stewart W C

Br J OphthalmolNov 200818 citationsRandomized Controlled Trial

Adding dorzolamide/timolol to latanoprost monotherapy provided the greatest 24-hour IOP reduction compared to switching to fixed combinations, offering a superior strategy for glaucoma patients needing enhanced pressure control.

8.

Twenty-four-hour efficacy of the brimonidine/timolol fixed combination versus therapy with the unfixed components.

Konstas A G P, Katsimpris I E, Kaltsos K, Georgiadou I, Kordelou A, Nelson L A et al.

Eye (Lond)Nov 200815 citationsRandomized Controlled Trial

This study found that brimonidine/timolol fixed combination and its unfixed components offer equivalent, significant 24-hour IOP reduction in glaucoma/ocular hypertension patients, simplifying treatment without compromising efficacy.

9.

Twenty-four-hour intraocular pressure and blood pressure levels with bimatoprost versus latanoprost in patients with normal-tension glaucoma.

Quaranta L, Pizzolante T, Riva I, Haidich A-B, Konstas A G P, Stewart W C

Br J OphthalmolSep 200837 citationsRandomized Controlled Trial

In normal-tension glaucoma, bimatoprost and latanoprost similarly lower 24-hour IOP. Latanoprost slightly improved ocular perfusion pressure, but both drugs yielded comparable overall perfusion and IOP reduction, offering similar clinical efficacy.

13.

Diurnal intraocular pressure reduction with latanoprost 0.005% compared to timolol maleate 0.5% as monotherapy in subjects with exfoliation glaucoma.

Konstas A G P, Mylopoulos N, Karabatsas C H, Kozobolis V P, Diafas S, Papapanos P et al.

Eye (Lond)Sep 200435 citationsRandomized Controlled Trial

This study found latanoprost provided better 8 AM intraocular pressure reduction and more stable diurnal pressure than timolol in exfoliation glaucoma, suggesting its potential for superior early-morning control.

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