Kremers Jan

Marmoy Oliver R, Tekavčič Pompe Manca, Kremers Jan

This review explored chromatic VEPs, finding their diverse methodologies limit clear clinical use despite potential for assessing color vision pathways in various eye diseases like glaucoma.

Huchzermeyer Cord, Lämmer Robert, Mardin Christian Y, Kruse Friedrich E, Kremers Jan, Horn Folkert K

This study found Pattern ERG (PERG) amplitude independently predicts visual field defect development in glaucoma suspects, offering a valuable tool for risk assessment and guiding early intervention.

Dussan Molinos Laura, Huchzermeyer Cord, Lämmer Robert, Kremers Jan, Horn Folkert K

A novel projector-based Blue-Yellow VEP system effectively detected early glaucoma by showing increased VEP latencies correlating with disease severity, offering a practical diagnostic tool.

Aher Avinash J, Horn Folkert K, Huchzermeyer Cord, Lämmer Robert, Kremers Jan

This study found glaucoma patients have reduced luminance-driven (L-add) ERG responses, but not cone-opponent responses, suggesting central luminance signals are primarily affected in glaucoma.

Huchzermeyer Cord, Horn Folkert, Lämmer Robert, Mardin Christian, Kremers Jan

This study found glaucoma primarily impairs the M-pathway's high-frequency contrast sensitivity, correlating with disease severity. P-pathway function and temporal processing phase angles remain intact.

Horn Folkert K, Scharch Vicki, Mardin Christian Y, Lämmer Robert, Kremers Jan

This study compared FDF and FDT perimetry in early glaucoma, finding both detect early disease. Combining these perimetry results with RNFL thickness improves overall detection, aiding early diagnosis.

Horn Folkert K, Kremers Jan, Mardin Christian Y, Jünemann Anselm G, Adler Werner, Tornow Ralf P

Flicker-defined form perimetry detected early glaucoma damage before standard tests, but its limited dynamic range means conventional perimetry is better for monitoring moderate-to-advanced disease.

Dutescu Ralf M, Skosyrski Sergej, Kociok Norbert, Semkova Irina, Mergler Stefan, Atorf Jenny et al.

This study optimized multifocal ERG in mice, finding it reliably detects and quantifies localized retinal damage (e.g., laser-induced) by correlating functional deficits with specific retinal areas, aiding therapeutic monitoring.

Horn Folkert K, Kaltwasser Christoph, Jünemann Anselm G, Kremers Jan, Tornow Ralf P

This study found objective multifocal VEPs correlated well with standard perimetry and RNFL thickness in glaucoma, especially in mid-peripheral areas. This offers a promising objective visual function assessment tool.

Barboni Mirella Telles Salgueiro, Pangeni Gobinda, Ventura Dora Fix, Horn Folkert, Kremers Jan

This study found glaucoma patients, even early cases, exhibit phase differences in flicker ERG responses reflecting both luminance and color pathways, suggesting early inner retinal dysfunction rather than amplitude changes.

Birke Marco T, Neumann Carolin, Birke Kerstin, Kremers Jan, Scholz Michael

This study found that osteopontin (OPN) levels in the aqueous humor of glaucoma model mice increased with age and correlated with optic nerve and RGC degeneration, suggesting its role in disease progression.