Lee Richard K

Rickels Kaersti L, Chauhan Muhammad Z, Saeedi Osamah J, Kishor Krishna S, Uwaydat Sami H, Bhattacharya Sanjoy K et al.

Diabetic retinopathy significantly increases lifetime OHT/POAG risk in T1DM (5x/4x) and T2DM (2.6x), especially with PDR. This mandates vigilant glaucoma screening and comprehensive ophthalmic management in all diabetic patients, particularly those with DR.

Abboud Ibrahim, Fam Anthony, Almobayed Amr, Guillaume Georges I, ElSheikh Reem H, Lee Richard K et al.

Abboud Ibrahim, Fam Anthony, Almobayed Amr, Guillaume Georges I, ElSheikh Reem H, Lee Richard K et al.

This study found pseudoexfoliation glaucoma (PXG) significantly increases the risk of central serous chorioretinopathy (CSCR) compared to primary open-angle glaucoma (POAG), suggesting shared posterior segment vascular susceptibility.

Ayoubi Mohammad, Sayed Mohamed S, Khodeiry Mohamed M, Elhusseiny Abdelrahman M, Lee Richard K

Big data in ophthalmology, using diverse databases, is transforming research by enabling AI, uncovering systemic links, and improving precision medicine for glaucoma and other conditions.

Sayed Mohamed S, Ayoubi Mohammad, Khodeiry Mohamed M, Elhusseiny Abdelrahman M, Lee Richard K

Elhusseiny Abdelrahman M, Eleiwa Taher K, Darwich Rami, Eadie Brennan, Etminan Mahyar, Chauhan Muhammad Z et al.

Chronic oral nitrate use in IHD patients was linked to a reduced risk of open-angle glaucoma, but not ocular hypertension, suggesting a potential protective effect against glaucoma development.

Elhusseiny Abdelrahman M, Eleiwa Taher K, Dihan Qais A, Chauhan Muhammad Z, Al'Aref Subhi J, Lee Richard K

Statin use was linked to reduced ocular hypertension/glaucoma risk in most racial groups, with varying effects and timing, highlighting racial disparities in treatment response.

Khodeiry Mohamed M, Yusuf Ramsey, Dorizas Christopher A, Elhusseiny Abdelrahman M, Sayed Mohamed S, Ruan Merry et al.

SC-TSCPC effectively lowers IOP in pseudoexfoliation glaucoma, offering a relatively safe, repeatable treatment option for medically uncontrolled cases, though further study is warranted.

Serhan Hashem Abu, Ba-Shammakh Saleh A, Hassan Amr K, Sanvicente Carina T, Anter Abdelrahman M, Marchi M Basil et al.

This review found trabeculectomy and tube shunts similarly reduced IOP in uveitic glaucoma, but tubes had more CME/revisions, while trabeculectomy had more cataract progression, guiding surgical choice.

Liu Yuan, Liu Xiangxiang, Dorizas Christopher A, Hao Zixuan, Lee Richard K

Studying optic nerve injury, researchers found depleting hematogenous macrophages reduced scar formation and preserved retinal ganglion cell function, suggesting a neuroprotective therapeutic strategy for optic nerve damage.

Chen Jessica L, Elhusseiny Abdelrahman M, Khodeiry Mohamed M, Smith Michael P, Sayed Mohamed S, Banitt Michael et al.

This study found that in complex glaucoma cases, corneal graft failure after GDI and PK is more common than GDI failure, implying IOP control isn't the sole determinant of graft survival.

Elhusseiny Abdelrahman M, Khodeiry Mohamed M, Liu Xiangxiang, Sayed Mohamed S, Lee Richard K

Slow-coagulation CW-TSCPC effectively lowered IOP and medication use in medically uncontrolled secondary aphakic glaucoma, offering a safe, non-incisional initial surgical option with a 63.4% success rate at one year.

Ma Rui, Hao Lili, Tao Yudong, Mendoza Ximena, Khodeiry Mohamed, Liu Yuan et al.

RGC-Net, a deep learning model, accurately and reliably reconstructs and quantifies retinal ganglion cell neurites and somas, offering a faster, automated tool for glaucoma analysis.

Elhusseiny Abdelrahman M, Yannuzzi Nicolas A, Khodeiry Mohamed M, Lee Richard K, Smiddy William E

Elhusseiny Abdelrahman M, Yannuzzi Nicolas A, Khodeiry Mohamed M, Lee Richard K, Smiddy William E

Khodeiry Mohamed M, Liu Xiangxiang, Lee Richard K

Slow-coagulation CW-TSCPC, a gentler laser technique, effectively and safely lowers intraocular pressure across various glaucoma types, offering a more controlled treatment option.

Khodeiry Mohamed M, Lauter Alison J, Sayed Mohamed S, Han Ying, Lee Richard K

Slow-coagulation TSCPC effectively lowered IOP and reduced medications in medically uncontrolled neovascular glaucoma, showing it's a safe and viable initial treatment option.

Elhusseiny Abdelrahman M, Yannuzzi Nicolas A, Khodeiry Mohamed M, Lee Richard K, Smiddy William E

This study found conventional glaucoma surgeries and SLT are more cost-efficient ($/mmHg IOP reduction) than minimally invasive options, suggesting they are preferable when cost is a significant concern.

Khodeiry Mohamed M, Liu Xiangxiang, Sheheitli Huda, Sayed Mohamed S, Lee Richard K

Slow coagulation TSCPC effectively and safely lowered intraocular pressure in patients with silicone oil-induced glaucoma, making it a viable initial surgical option with minimal complications.

Xing Xiaoli, Tong Xiaowei, Liu Yuan, Tapia Mary, Jin Peiyao, Holley Timothy D et al.

This study developed a laser-induced mouse model for traumatic optic neuropathy, reliably causing retinal ganglion cell death and functional loss without side effects. This model is useful for studying RGC death and testing neuroprotective therapies.

Ma Rui, Liu Yuan, Tao Yudong, Alawa Karam A, Shyu Mei-Ling, Lee Richard K

A deep learning model accurately and automatically measured retinal nerve fiber layer thickness in mouse OCTs, offering a reliable, faster alternative to manual segmentation for glaucoma research.

Khodeiry Mohamed M, Sheheitli Huda, Sayed Mohamed S, Persad Patrice J, Feuer William J, Lee Richard K

Slow coagulation TSCPC effectively lowered IOP and medication use in pseudophakic glaucoma patients, especially with higher baseline IOP, showing good safety as an initial treatment.

Zhai Ruyi, Cheng Jingyi, Xu Huan, Fang Zhaobin, Chen Xu, Qiu Siyu et al.

This study found a new parameter, MAPE, effectively quantifies 24-hour IOP fluctuations. Higher in glaucoma patients, MAPE better correlated with visual field damage, offering a valuable clinical tool for glaucoma assessment.

Alawa Karam AlRahman, Nolan Ryan P, Han Elaine, Arboleda Alejandro, Durkee Heather, Sayed Mohamed S et al.

A smartphone-based glaucoma visual field test (MVP FDT) was comparable to standard, expensive equipment. This offers a low-cost, portable, and accessible screening tool for glaucoma.

Sayed Mohamed S, Lee Richard K

This abstract reviews XFG surgical options, finding cataract surgery significantly lowers IOP and may prevent glaucoma, while newer MIGS and non-penetrating surgeries are emerging, expanding treatment choices.