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Anatomy- versus Sensitivity-Based Loci Preselection in Detecting USH2A-Retinopathy Microperimetric Progression.
Charng Jason, Alonso-Caneiro David, Lamey Tina M, Thompson Jennifer A, Lim Jeremiah K H, Ong Elaine et al.
Ophthalmol SciNov 20250 citationsCohort Study
This study compared microperimetry progression methods in USH2A-retinopathy. Sensitivity-based (mFTP) and anatomy-based (HRS) point selections best detected progression, outperforming overall and scotoma-edge sensitivity. This improves monitoring for clinical trials.