Wong Vickie H Y

Ganearachchi Sera N, Zhao Da, Wong Vickie H Y, Lee Pei Ying, Afiat Brianna C, Nguyen Christine T O et al.

This rat study found that reducing optic nerve sheath pressure worsened optic nerve damage from elevated eye pressure, suggesting CSF pressure is crucial in glaucoma.

Zhao Da, He Zheng, Wang Lin, Fortune Brad, Lim Jeremiah K H, Wong Vickie H Y et al.

This study found intermediate and deep retinal vessels in rats are more resistant to mild IOP elevation than superficial vessels, but all layers are affected by high IOP.

Zhao Da, Wong Vickie H Y, Nguyen Christine T O, Jobling Andrew I, Fletcher Erica L, Vingrys Algis J et al.

This mouse study found that retinal ganglion cell dysfunction from chronic IOP elevation was reversible after 8 weeks but irreversible after 12 weeks, highlighting the importance of early glaucoma intervention.

Wong Vickie H Y, Vingrys Algis J, Jobling Andrew I, Bui Bang V

Diabetic rats showed increased retinal vulnerability and impaired ocular blood flow autoregulation under high IOP, linked to reduced eNOS upregulation, suggesting diabetes exacerbates glaucoma risk.