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Valproic Acid Application to Modify Post Surgical Fibrosis in a Model of Minimally Invasive Bleb Surgery.
Lo Phey Feng, Gunawan Merry, Yap Zhu Li, Leong Carol, Kwek Fuxuan, Varadarajan Jayasudha et al.
Transl Vis Sci TechnolJun 20251 citationsBasic Science
Valproic acid, combined with low-dose MMC, improved bleb survival and reduced fibrosis after minimally invasive glaucoma surgery in rabbits. This suggests VPA could be a safe, versatile antifibrotic agent.