Lotery Andrew J

Warwick Alasdair N, Curran Katie, Hamill Barbra, Stuart Kelsey, Khawaja Anthony P, Foster Paul J et al.

UK Biobank retinal imaging of 68,514 participants identified glaucoma features in 2184, with 8.6% having a prior diagnosis. This dataset provides valuable insights for ocular and systemic health research.

Akyol Engin, Hagag Ahmed M, Sivaprasad Sobha, Lotery Andrew J

Adaptive optics allows cellular-level retinal imaging, revealing disease mechanisms. While a powerful research tool, clinical use is currently limited by cost, scan time, and small imaging area.

Hallam Thomas M, Marchbank Kevin J, Harris Claire L, Osmond Clive, Shuttleworth Victoria G, Griffiths Helen et al.

This study confirmed rare genetic CFI variants cause low systemic FI levels, strongly increasing AMD risk, highlighting challenges for therapeutic FI replacement due to ocular impermeability.

Chua Sharon Y L, Khawaja Anthony P, Dick Andrew D, Morgan James, Dhillon Baljean, Lotery Andrew J et al.

Ambient air pollution was linked to altered retinal layer thicknesses, suggesting a potential structural impact on the eye from environmental factors relevant to glaucoma and AMD.

Ko Fang, Foster Paul J, Strouthidis Nicholas G, Shweikh Yusrah, Yang Qi, Reisman Charles A et al.

This study found RPE-BM thickness varies with age, ethnicity, refraction, IOP, and smoking. IOP's association suggests relevance for glaucoma etiology, while age and smoking may impact AMD.