Strouthidis Nicholas G

Sun Zihan, Stuart Kelsey V, Luben Robert N, Auld Amy L, Strouthidis Nicholas G, Khaw Peng T et al.

This study found higher exposure to fine particulate air pollution (PM2.5) significantly increases glaucoma risk, highlighting air quality's public health impact on eye health and the need for interventions.

Baker N Douglas, Barnebey Howard S, Moster Marlene R, Stiles Michael C, Vold Steven D, Khatana Anup K et al.

This study compared MicroShunt and trabeculectomy for glaucoma; trabeculectomy achieved better IOP reduction and success rates, making it more effective at one year.

Wang Xiaofei, Tun Tin A, Nongpiur Monisha Esther, Htoon Hla M, Tham Yih Chung, Strouthidis Nicholas G et al.

This study found the peripapillary sclera's v-shaped configuration is more pronounced in glaucoma eyes, suggesting this posterior bowing impacts optic nerve head biomechanics, potentially aiding early detection or understanding disease progression.

Tun Tin A, Wang Xiaofei, Baskaran Mani, Nongpiur Monisha Esther, Tham Yih Chung, Nguyen Duc Quang et al.

This study found lamina cribrosa depth varies by age, gender, race, and ocular factors in healthy Asians. This normative data aids more accurate glaucoma assessment via OCT.

Jayaram Hari, Strouthidis Nicholas G, Gazzard Gus

Chua Sharon Y L, Khawaja Anthony P, Dick Andrew D, Morgan James, Dhillon Baljean, Lotery Andrew J et al.

Ambient air pollution was linked to altered retinal layer thicknesses, suggesting a potential structural impact on the eye from environmental factors relevant to glaucoma and AMD.

Zhang Liang, Beotra Meghna R, Baskaran Mani, Tun Tin A, Wang Xiaofei, Perera Shamira A et al.

This study measured optic nerve head tissue stiffness in vivo, finding healthy prelamina significantly softer than in ocular hypertension, suggesting biomechanics may aid glaucoma management.

Vennam Sarath, Georgoulas Stelios, Khawaja Anthony, Chua Sharon, Strouthidis Nicholas G, Foster Paul J

This review explores if heavy metal toxicity contributes to glaucoma, finding plausible links due to shared neurodegenerative mechanisms, suggesting environmental exposures may impact eye health.

Devalla Sripad Krishna, Liang Zhang, Pham Tan Hung, Boote Craig, Strouthidis Nicholas G, Thiery Alexandre H et al.

This review explored AI's role in glaucoma diagnosis and prognosis. It found AI offers promising tools to improve early detection and predict disease progression, potentially aiding clinical management.

Tun Tin A, Wang Xiaofei, Baskaran Mani, Nongpiur Monisha E, Tham Yih-Chung, Perera Shamira A et al.

This study found the peripapillary sclera becomes more v-shaped (orbital peak) with age, potentially impacting optic nerve head biomechanics.

Tun Tin A, Atalay Eray, Baskaran Mani, Nongpiur Monisha E, Htoon Hla M, Goh David et al.

This study found that optic nerve head biomechanical changes from acute IOP elevation correlated with visual field loss in POAG, suggesting ONH biomechanics relate to disease severity and differ between glaucoma types.

Devalla Sripad Krishna, Chin Khai Sing, Mari Jean-Martial, Tun Tin A, Strouthidis Nicholas G, Aung Tin et al.

A deep learning algorithm accurately digitally stained optic nerve head OCT layers in healthy and glaucoma eyes, enabling automated structural measurements crucial for improved glaucoma management.

Beotra Meghna R, Wang Xiaofei, Tun Tin A, Zhang Liang, Baskaran Mani, Aung Tin et al.

This study found that ocular hypertensive eyes exhibit lower lamina cribrosa strain than healthy eyes following acute IOP elevation, suggesting structural differences in glaucoma susceptibility.

Sharma Sourabh, Tun Tin A, Baskaran Mani, Atalay Eray, Thakku Sri Gowtham, Liang Zhang et al.

Acute IOP elevation compressed the optic nerve rim in glaucoma patients, but not in normal or OHT eyes, indicating glaucoma optic nerves are more susceptible to IOP changes.

Ko Fang, Foster Paul J, Strouthidis Nicholas G, Shweikh Yusrah, Yang Qi, Reisman Charles A et al.

This study found RPE-BM thickness varies with age, ethnicity, refraction, IOP, and smoking. IOP's association suggests relevance for glaucoma etiology, while age and smoking may impact AMD.

Wang Xiaofei, Beotra Meghna R, Tun Tin Aung, Baskaran Mani, Perera Shamira, Aung Tin et al.

This study found horizontal eye movements cause significant optic nerve head strains, comparable to those from acute IOP elevation. This suggests eye movement-induced strain might contribute to optic nerve damage.

Jayaram Hari, Scawn Richard, Pooley Francisco, Chiang Mark, Bunce Catey, Strouthidis Nicholas G et al.

MMC-augmented trabeculectomy in infants showed good long-term glaucoma control (60% at 7 years) with low complications, offering a promising option for early childhood glaucoma management, often without medication.

Jayaram Hari, Strouthidis Nicholas G, Kamal Deborah S

Trabeculectomy for normal tension glaucoma, using modern techniques, showed excellent long-term success and fewer complications than previously reported, offering a valuable treatment option.

Thakku Sri Gowtham, Tham Yih-Chung, Baskaran Mani, Mari Jean-Martial, Strouthidis Nicholas G, Aung Tin et al.

This study developed a new lamina cribrosa shape index (LC-GSI). A more prominent central ridge (larger LC-GSI) was linked to shorter axial length and smaller VCDR, suggesting its potential role in glaucoma risk assessment.

Tun Tin A, Sun Chen-Hsin, Baskaran Mani, Girard Michael J A, de Leon John Mark S, Cheng Ching-Yu et al.

This study found optic disc area and rim area are the strongest determinants of BMO-MRW in normal Chinese eyes, providing a crucial normative database for glaucoma diagnosis.

Tham Yih-Chung, Cheung Carol Y, Koh Victor T, Cheng Ching-Yu, Sidhartha Elizabeth, Strouthidis Nicholas G et al.

This study found only fair correlations between macular GC-IPL and optic disc/RNFL parameters in healthy eyes, suggesting GC-IPL provides additional, distinct information for glaucoma detection.

Wang Ya Xing, O'Leary Neil, Strouthidis Nicholas G, White Edward T, Ho Tuan A, Garway-Heath David F

This study compared neuroretinal rim area measurements between HRT I and HRT II. It found significant differences when using HRT I as a baseline for HRT II follow-up, impacting glaucoma progression tracking when switching devices.

Mari Jean Martial, Strouthidis Nicholas G, Park Sung Chul, Girard Michaël J A

An adaptive OCT algorithm improved lamina cribrosa posterior boundary visibility by reducing noise. This enhances glaucoma diagnosis and monitoring by better characterizing optic nerve head biomechanics.

Yang Hongli, Qi Jingjing, Hardin Christy, Gardiner Stuart K, Strouthidis Nicholas G, Fortune Brad et al.

EDI significantly improved visibility of the optic nerve's posterior lamina cribrosa in nonhuman primates, especially in glaucoma, potentially aiding earlier disease detection and monitoring.

Strouthidis Nicholas G, Fortune Brad, Yang Hongli, Sigal Ian A, Burgoyne Claude F

Acute IOP elevation in monkeys significantly deformed the ONH, reducing prelaminar tissue/rim volume and increasing NCO/ALCS depth. This shows how IOP impacts ONH biomechanics, aiding glaucoma understanding.