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Boote Craig

10 articles in GJC

10 articles in GJC

1.

Deep learning algorithms to isolate and quantify the structures of the anterior segment in optical coherence tomography images.

Pham Tan Hung, Devalla Sripad Krishna, Ang Aloysius, Soh Zhi-Da, Thiery Alexandre H, Boote Craig et al.

Br J OphthalmolSep 202029 citationsBasic Science

Deep learning accurately identified anterior segment structures and quantified key measurements from OCT images, matching expert performance for glaucoma diagnosis and management, offering rapid, reliable automation.

4.

Morphometric, Hemodynamic, and Biomechanical Factors Influencing Blood Flow and Oxygen Concentration in the Human Lamina Cribrosa.

Chuangsuwanich Thanadet, Hung Pham Tan, Wang Xiaofei, Liang Leo Hwa, Schmetterer Leopold, Boote Craig et al.

Invest Ophthalmol Vis SciApr 202023 citationsBasic Science

This study modeled lamina cribrosa oxygen levels, finding LC radius and perfusion pressure are key. Higher IOP slightly lowers oxygen, suggesting biomechanical and vascular factors contribute to glaucoma's optic nerve damage.

5.

Effect of Changing Heart Rate on the Ocular Pulse and Dynamic Biomechanical Behavior of the Optic Nerve Head.

Jin Yuejiao, Wang Xiaofei, Irnadiastputri Sylvi Febriana Rachmawati, Mohan Rosmin Elsa, Aung Tin, Perera Shamira A et al.

Invest Ophthalmol Vis SciApr 202011 citationsBasic Science

A model showed increasing heart rate decreased ocular pulse and ONH deformation, while stiffening the lamina cribrosa. This suggests heart rate impacts ONH biomechanics, relevant for glaucoma pathology.

9.

Quantitative mapping of collagen fiber orientation in non-glaucoma and glaucoma posterior human sclerae.

Pijanka Jacek K, Coudrillier Baptiste, Ziegler Kimberly, Sorensen Thomas, Meek Keith M, Nguyen Thao D et al.

Invest Ophthalmol Vis SciAug 2012127 citationsBasic Science

This study mapped collagen fiber orientation in human sclera, finding reduced peripapillary fiber anisotropy in glaucoma eyes. This suggests structural differences may impact glaucoma susceptibility or progression.

10.

The influence of lamellar orientation on corneal material behavior: biomechanical and structural changes in an avian corneal disorder.

Boote Craig, Elsheikh Ahmed, Kassem Wael, Kamma-Lorger Christina S, Hocking Paul M, White Nick et al.

Invest Ophthalmol Vis SciMar 201114 citationsBasic Science

This study found that abnormal corneal collagen orientation in diseased chicken eyes increased stiffness, highlighting how structural changes impact corneal biomechanics and its response to intraocular pressure.

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