Girard Michael J A

Liu Tingting, Wang Kehao, Wang Ya Xing, Liu Xiaoyu, Han Jingyun, Girard Michael J A et al.

Ciliary muscle traction during accommodation causes significant optic nerve head deformation, comparable to high eye pressure, especially with stiffer choroid/Bruch's membrane, potentially impacting glaucoma progression.

Fisher Liam K, Wang Xiaofei, Tun Tin A, Chung Hsi-Wei, Milea Dan, Girard Michael J A

This study found that thyroid eye disease (TED), particularly with proptosis or stiff extraocular tissue, significantly increases gaze-evoked optic nerve head deformations. This suggests a potential mechanism for optic neuropathy in TED.

Pham Tan Hung, Devalla Sripad Krishna, Ang Aloysius, Soh Zhi-Da, Thiery Alexandre H, Boote Craig et al.

Deep learning accurately identified anterior segment structures and quantified key measurements from OCT images, matching expert performance for glaucoma diagnosis and management, offering rapid, reliable automation.

Bak Eunoo, Lee Won June, Kim Jin-Soo, Lee Jinho, Ha Ahnul, Kim Yong Woo et al.

This study found that glaucoma patients with a laminar dot sign have thinner prelaminar tissue and a significantly higher risk of disease progression, indicating a more vulnerable optic nerve.

Zhang Liang, Beotra Meghna R, Baskaran Mani, Tun Tin A, Wang Xiaofei, Perera Shamira A et al.

This study measured optic nerve head tissue stiffness in vivo, finding healthy prelamina significantly softer than in ocular hypertension, suggesting biomechanics may aid glaucoma management.

Devalla Sripad Krishna, Liang Zhang, Pham Tan Hung, Boote Craig, Strouthidis Nicholas G, Thiery Alexandre H et al.

This review explored AI's role in glaucoma diagnosis and prognosis. It found AI offers promising tools to improve early detection and predict disease progression, potentially aiding clinical management.

Fazio Massimo A, Girard Michael J A, Lee Wonyul, Morris Jeffrey S, Burgoyne Claude F, Downs J Crawford

This NHP study found scleral mechanical properties change with cumulative IOP exposure, initially becoming more compliant then stiffer. This suggests IOP-induced scleral remodeling impacts glaucoma.

Boote Craig, Sigal Ian A, Grytz Rafael, Hua Yi, Nguyen Thao D, Girard Michael J A

This review highlights advances in understanding scleral structure and biomechanics, showing how age and diseases like glaucoma alter it. This knowledge is crucial for developing new therapies for vision disorders.

Kim Ji-Ah, Kim Tae-Woo, Lee Eun Ji, Girard Michael J A, Mari Jean Martial

This study found that increased lamina cribrosa curvature correlated with reduced blood flow in normal-tension glaucoma eyes, suggesting mechanical stress impairs ocular perfusion in this condition.

Park Ji-Hye, Yoo Chungkwon, Girard Michael J A, Mari Jean-Martial, Kim Yong Yeon

This study found peripapillary vessel density is lower in pseudoexfoliation glaucoma than primary open-angle glaucoma of similar severity, suggesting distinct vascular compromise in PXG.

Ha Ahnul, Kim Tai Jun, Girard Michael J A, Mari Jean Martial, Kim Young Kook, Park Ki Ho et al.

This study found greater baseline posterior bowing of the lamina cribrosa correlated with faster visual field deterioration in POAG, suggesting increased vulnerability to glaucomatous injury.

Lee Won June, Kim Hae Jin, Park Ki Ho, Kim Yong Woo, Girard Michael J A, Mari Jean Martial et al.

Nagia Lina, Huisingh Carrie, Johnstone John, Kline Lanning B, Clark Mark, Girard Michael J A et al.

NAION and contralateral eyes showed thicker peripapillary choroids than normal eyes. This suggests a thickened choroid might contribute to the "disk-at-risk" phenotype for NAION.

Kim Dai Woo, Jeoung Jin Wook, Kim Yong Woo, Girard Michael J A, Mari Jean Martial, Kim Young Kook et al.

This study found that even unaffected fellow eyes in unilateral glaucoma patients show subclinical lamina cribrosa and prelaminar tissue thinning, suggesting early, pre-symptomatic changes.

Nongpiur Monisha E, Png Owen, Chiew Jestin W, Fan Kenric R, Girard Michael J A, Wong Tina et al.

This study found corneal biomechanical parameters (CH, CRF) are not associated with glaucoma severity in primary angle closure glaucoma, meaning they don't predict disease progression.

Thakku Sri Gowtham, Tham Yih-Chung, Baskaran Mani, Mari Jean-Martial, Strouthidis Nicholas G, Aung Tin et al.

This study developed a new lamina cribrosa shape index (LC-GSI). A more prominent central ridge (larger LC-GSI) was linked to shorter axial length and smaller VCDR, suggesting its potential role in glaucoma risk assessment.

Tun Tin A, Sun Chen-Hsin, Baskaran Mani, Girard Michael J A, de Leon John Mark S, Cheng Ching-Yu et al.

This study found optic disc area and rim area are the strongest determinants of BMO-MRW in normal Chinese eyes, providing a crucial normative database for glaucoma diagnosis.

Rhodes Lindsay A, Huisingh Carrie, Johnstone John, Fazio Massimo A, Smith Brandon, Wang Lan et al.

This study found peripapillary choroidal thickness varies with age and race; African-descended individuals have thicker choroids than European-descended, and thickness decreases with age. This informs glaucoma risk assessment.

Fazio Massimo A, Grytz Rafael, Bruno Luigi, Girard Michael J A, Gardiner Stuart, Girkin Christopher A et al.

This study found peripapillary sclera experiences higher strain than mid-peripheral, particularly inferotemporally, which may explain glaucoma damage patterns.