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Morris Jeffrey S

3 articles in GJC

3 articles in GJC

1.

Intra-Subject Variability and Diurnal Cycle of Ocular Perfusion Pressure as Characterized by Continuous Telemetry in Nonhuman Primates.

Wilson Katherine I, Godara Pooja, Jasien Jessica V, Zohner Emma, Morris Jeffrey S, Girkin Christopher A et al.

Invest Ophthalmol Vis SciJun 20206 citationsBasic Science

Continuous telemetry in NHPs revealed wide individual differences and varied diurnal OPP cycles, including lower OPP during sleep for most. This highlights that single measurements are insufficient and supports NHP glaucoma research.

2.

The Relationship Between Scleral Strain Change and Differential Cumulative Intraocular Pressure Exposure in the Nonhuman Primate Chronic Ocular Hypertension Model.

Fazio Massimo A, Girard Michael J A, Lee Wonyul, Morris Jeffrey S, Burgoyne Claude F, Downs J Crawford

Invest Ophthalmol Vis SciOct 201911 citationsBasic Science

This NHP study found scleral mechanical properties change with cumulative IOP exposure, initially becoming more compliant then stiffer. This suggests IOP-induced scleral remodeling impacts glaucoma.

3.

Transient Intraocular Pressure Fluctuations: Source, Magnitude, Frequency, and Associated Mechanical Energy.

Turner Daniel C, Edmiston Anna M, Zohner Ye Emma, Byrne Kevin J, Seigfreid William P, Girkin Christopher A et al.

Invest Ophthalmol Vis SciJun 201958 citationsBasic Science

This study found that transient IOP fluctuations from blinks, saccades, and ocular pulse are frequent (10,000/hour), large (up to 14 mmHg), and contribute significantly (12%) to total ocular mechanical stress, suggesting single IOP measurements are insufficient.

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