Girkin Christopher A

Girkin Christopher A, Walker Evan, Gardiner Stuart K, Hallaj Shahin, Murillo Karla, Jiravarnsirikul Anuwat et al.

Progressive posterior lamina cribrosa remodeling predicts faster visual field progression in glaucoma. This structural-functional link is modulated by age, CCT, and IOP, suggesting varying biomechanical responses to glaucomatous stress.

Antwi-Adjei Ellen K, Swain Thomas A, Girkin Christopher A, Owsley Cynthia, Rhodes Lindsay A, Racette Lyne

Tablet-based perimetry (MRF) showed moderate agreement with standard HFA for visual field indices. This suggests potential for telemedicine glaucoma screening and monitoring in underserved rural areas, despite HFA having higher fixation losses.

Huang Alex S, Garner Mary Anne, Clark Mark E, Rhodes Lindsay A, Kallab Martin, Zhang Hao F et al.

Cholinergic stimulation improved aqueous humor outflow in specific, low-flow regions of human eyes, suggesting potential for targeted glaucoma treatments.

Gunasegaran Gopikasree, Moghimi Sasan, Nishida Takashi, Liebmann Jeffrey M, Fazio Massimo A, Girkin Christopher A et al.

This study found central visual field progression identified more fast progressors across all glaucoma stages than global measures, highlighting the need to monitor central vision closely.

Chuter Benton, Joshi Vedant, Hallaj Shahin, Walker Evan, Bowd Christopher, Belghith Akram et al.

A novel AI model for glaucoma detection showed multimodal imaging (CFP + OCT) was better than CFP alone, but not significantly better than OCT alone, suggesting OCT-based AI may suffice clinically.

Nishida Takashi, Weinreb Robert N, Walker Evan, Girkin Christopher A, Fazio Massimo A, Liebmann Jeffrey M et al.

This study compared visual field progression methods in glaucoma patients with central defects, finding 10-2 VF tests detected more central progression, highlighting 24-2 VF alone may underestimate it.

Jalili Jalil, Huynh Justin, Walker Evan, Chuter Benton Gabriel, Bowd Christopher, Heinke Anna et al.

Fine-tuned vision-language models effectively detected glaucoma and predicted visual field loss from OCT images, showing promise for scalable AI decision support in glaucoma care, matching or exceeding specialized models.

Fazio Massimo A, Gardiner Stuart K, Moreno K S Reynoso, Clark Mark E, Girkin Christopher A

Higher RPC density correlates with better visual fields in POAG. OCT-A RPC density is a valuable, consistent biomarker for glaucoma severity, with comparable diagnostic performance between SD-OCT and SS-OCT platforms.

Pham Vincent Q, Nishida Takashi, Moghimi Sasan, Alam Naimul, Girkin Christopher A, Fazio Massimo A et al.

Initial OCT-measured cpRNFL loss rates predict future glaucoma progression, with faster early loss indicating higher risk. This helps clinicians predict disease course and guide patient management.

Gunasegaran Gopikasree, Moghimi Sasan, Walker Evan, Nishida Takashi, Liebmann Jeffrey M, Fazio Massimo A et al.

This study found central visual field progression impacts glaucoma patients' quality of life more than global progression, suggesting current assessments may underestimate patient-centered outcomes.

Seo Je Hyun, Nishida Takashi, Moghimi Sasan, Wu Jo-Hsuan, Fazio Massimo A, Girkin Christopher A et al.

This study found higher physical activity levels independently slowed visual field loss in glaucoma patients, suggesting exercise may protect against disease progression.

Pham Vincent Q, Nishida Takashi, Moghimi Sasan, Girkin Christopher A, Fazio Massimo A, Liebmann Jeffrey M et al.

This study found that both higher average blood pressure and greater blood pressure variability are associated with faster visual field progression in glaucoma, suggesting BP management is crucial.

Chuter Benton, Huynh Justin, Hallaj Shahin, Walker Evan, Liebmann Jeffrey M, Fazio Massimo A et al.

This study found an AI model (RETFound) effectively detects glaucoma from fundus photos, improving with more training data and performing consistently across diverse populations, making it a promising diagnostic tool.

Wu Jo-Hsuan, Moghimi Sasan, Walker Evan, Nishida Takashi, Liebmann Jeffrey M, Fazio Massimo A et al.

In individuals of African descent, OCT (RNFLT) detected glaucoma progression significantly earlier than visual fields, supporting its importance for monitoring this population.

Wu Jo-Hsuan, Moghimi Sasan, Walker Evan, Nishida Takashi, Liebmann Jeffrey M, Fazio Massimo A et al.

This study found long-term retinal nerve fiber layer thickness variability is small in glaucoma patients of African and European descent. Cataract surgery was the strongest predictor of variability; excluding it eliminated racial differences, suggesting RNFLT reliability across races.

Balakrishnan Poojitha, Swain Thomas A, McGwin Gerald, Owsley Cynthia, Girkin Christopher A, Rhodes Lindsay A

This study compared glaucoma diagnosis agreement between telemedicine, in-person ophthalmologists, and optometrists. Telemedicine showed moderate agreement, suggesting its utility for glaucoma screening and increasing access to care, especially in remote areas.

Mahmoudinezhad Golnoush, Moghimi Sasan, Nishida Takashi, Walker Evan, Latif Kareem, Liebmann Jeffrey M et al.

This study found higher long-term IOP variability, not just mean IOP, independently linked to faster retinal ganglion cell thinning in glaucoma, suggesting it's a key therapeutic target.

Girkin Christopher A, Owsley Cynthia

Existing retail and FQHC settings can effectively screen at-risk populations for glaucoma using telemedicine, showing high prevalence and diagnostic agreement, offering a scalable, cost-effective detection strategy.

Chuter Benton, Huynh Justin, Bowd Christopher, Walker Evan, Rezapour Jasmin, Brye Nicole et al.

A deep learning model accurately assessed fundus photo quality, and filtering out low-quality images significantly improved automated glaucoma detection, enhancing efficiency and accuracy in clinical screening.

Wu Jo-Hsuan, Moghimi Sasan, Walker Evan, Nishida Takashi, Brye Nicole, Mahmoudinezhad Golnoush et al.

This study found that while OCT glaucoma progression detection time is similar across races with identical thinning, it's shorter in African Descent eyes due to faster real-world thinning rates. This suggests OCT may detect progression more consistently across races than visual fields.

Girkin Christopher A, Garner Mary A, Gardiner Stuart K, Clark Mark E, Hubbard Meredith, Karuppanan Udayakumar et al.

This study found that lamina cribrosa displacement due to acute IOP elevation in deceased donors decreases with age and varies significantly based on the measurement reference plane, highlighting a need for standardized OCT metrics.

KhalafAllah Mahmoud T, Zangwill Linda M, Proudfoot James, Walker Evan, Girkin Christopher A, Fazio Massimo A et al.

OCT RNFLT diagnostic accuracy for glaucoma is lower in individuals of African descent than European descent, highlighting racial differences impacting clinical interpretation.

Owsley Cynthia, Swain Thomas A, McGwin Gerald, Nghiem Van Thi Ha, Register Shilpa, Asif Irfan M et al.

Telemedicine screening in FQHCs detected high rates of treatable eye conditions (30% glaucoma, 37.6% cataract), with good follow-up attendance (76.7%) and high patient satisfaction, showing its effectiveness and scalability.

Hong Seungwoo, Yang Hongli, Gardiner Stuart K, Luo Haomin, Sharpe Glen P, Caprioli Joseph et al.

This study found that optic nerve head remodeling in non-highly myopic eyes correlates with exposed scleral flange and thin choroid, suggesting implications for glaucoma risk, especially in high myopia.

Wu Jo-Hsuan, Moghimi Sasan, Walker Evan, Nishida Takashi, Liebmann Jeffrey M, Fazio Massimo et al.

This study identified factors increasing OCT variability in glaucoma, like African American race, cataract/glaucoma surgery, and faster RNFL thinning. More frequent testing reduced variability, improving progression detection.