Zangwill Linda M

Girkin Christopher A, Walker Evan, Gardiner Stuart K, Hallaj Shahin, Murillo Karla, Jiravarnsirikul Anuwat et al.

Progressive posterior lamina cribrosa remodeling predicts faster visual field progression in glaucoma. This structural-functional link is modulated by age, CCT, and IOP, suggesting varying biomechanical responses to glaucomatous stress.

Suh Min Hee, Weinreb Robert N, Hallaj Shahin, Zangwill Linda M

Optic disc microvasculature reduction is strongly associated with visual field progression in all stages of glaucoma. This suggests OCTA can help detect glaucoma worsening, even in advanced cases.

Hallaj Shahin, Boland Michael V, Halfpenny William, Myers Jonathan S, Weinreb Robert N, Zangwill Linda M et al.

PyOPV parses diverse ophthalmic visual field DICOM data into research formats, despite significant vendor tag variability (17-51% missing). This enables scalable integration for large-scale glaucoma research, overcoming interoperability challenges.

Gunasegaran Gopikasree, Moghimi Sasan, Nishida Takashi, Liebmann Jeffrey M, Fazio Massimo A, Girkin Christopher A et al.

This study found central visual field progression identified more fast progressors across all glaucoma stages than global measures, highlighting the need to monitor central vision closely.

Wu Jo-Hsuan, Nishida Takashi, Moghimi Sasan, Walker Evan, Zangwill Linda M, Weinreb Robert N

This study found no racial difference in glaucoma progression detection time using OCT/OCTA. However, OCTA detected progression faster than OCT in both African and European descendants, suggesting its potential to enhance monitoring.

Suh Min Hee, Weinreb Robert N, Walker Evan, Zangwill Linda M

In highly myopic glaucoma, progressive optic disc vessel density reduction, not RNFL thinning, predicted visual field progression. Monitoring microvasculature may better detect progression in these patients.

Pham Vincent Q, Nishida Takashi, Moghimi Sasan, Alam Naimul, Girkin Christopher A, Fazio Massimo A et al.

Initial OCT-measured cpRNFL loss rates predict future glaucoma progression, with faster early loss indicating higher risk. This helps clinicians predict disease course and guide patient management.

Belghith Akram, Bowd Christopher, Weinreb Robert N, Jalili Jalil, Christopher Mark, Zangwill Linda M

3D deep learning models accurately detect glaucoma, outperforming GCIPL thickness. Cross-domain models, using synthetic data, perform similarly, suggesting broader applicability across different OCT devices.

Soltani Ghazaleh, Nishida Takashi, Moghimi Sasan, Tran Elaine, Yamane Maya, Girkin Christopher et al.

This study found optic nerve head prelaminar schisis, especially severe forms, is linked to faster visual field loss in glaucoma, suggesting it's a biomarker for progression risk.

Gunasegaran Gopikasree, Moghimi Sasan, Walker Evan, Nishida Takashi, Liebmann Jeffrey M, Fazio Massimo A et al.

This study found central visual field progression impacts glaucoma patients' quality of life more than global progression, suggesting current assessments may underestimate patient-centered outcomes.

Seo Je Hyun, Nishida Takashi, Moghimi Sasan, Wu Jo-Hsuan, Fazio Massimo A, Girkin Christopher A et al.

This study found higher physical activity levels independently slowed visual field loss in glaucoma patients, suggesting exercise may protect against disease progression.

Wu Jo-Hsuan, Moghimi Sasan, Nishida Takashi, Adelpour Mohsen, Kamalipour Alireza, Gunasegaran Gopikasree et al.

This study found optic nerve head microvasculature loss occurs earlier and correlates better with visual field damage than macular loss in glaucoma, suggesting OCTA can monitor early disease.

Suh Min Hee, Weinreb Robert N, Walker Evan, Zangwill Linda M

This study found optic disc microvasculature reduction is strongly linked to visual field progression in glaucoma, suggesting deep optic nerve circulation plays a key role in disease worsening.

Pham Vincent Q, Nishida Takashi, Moghimi Sasan, Girkin Christopher A, Fazio Massimo A, Liebmann Jeffrey M et al.

This study found that both higher average blood pressure and greater blood pressure variability are associated with faster visual field progression in glaucoma, suggesting BP management is crucial.

Nishida Takashi, Moghimi Sasan, Gunasegaran Gopikasree, Walker Evan, Wu Jo-Hsuan, Rahmatnejad Kamran et al.

Metformin use in glaucoma patients was linked to thicker retinal nerve fiber layer and higher capillary density, suggesting a potential protective effect warranting further study.

Jalili Jalil, Jiravarnsirikul Anuwat, Bowd Christopher, Chuter Benton, Belghith Akram, Goldbaum Michael H et al.

GPT-4V analyzed fundus images for glaucoma detection and features. It showed promise, with variable agreement to experts, suggesting potential for screening but needing refinement for clinical use.

Gordon Mae O, Gao Feng, Burkland John, Huecker Julia B, Gardiner Stuart K, Ramulu Pradeep et al.

This study found preperimetric glaucoma doesn't reduce quality of life, but visual field loss does. This suggests clinicians can delay aggressive treatment for early glaucoma without visual field loss.

Nishida Takashi, Moghimi Sasan, Jin Wang, Zangwill Linda M, Weinreb Robert N

Atrial fibrillation and related microvascular damage were linked to slightly faster visual field loss in glaucoma patients, highlighting the need to manage cardiovascular risk factors.

Chuter Benton, Huynh Justin, Hallaj Shahin, Walker Evan, Liebmann Jeffrey M, Fazio Massimo A et al.

This study found an AI model (RETFound) effectively detects glaucoma from fundus photos, improving with more training data and performing consistently across diverse populations, making it a promising diagnostic tool.

Wu Jo-Hsuan, Moghimi Sasan, Walker Evan, Nishida Takashi, Liebmann Jeffrey M, Fazio Massimo A et al.

In individuals of African descent, OCT (RNFLT) detected glaucoma progression significantly earlier than visual fields, supporting its importance for monitoring this population.

Wu Jo-Hsuan, Moghimi Sasan, Walker Evan, Nishida Takashi, Liebmann Jeffrey M, Fazio Massimo A et al.

This study found long-term retinal nerve fiber layer thickness variability is small in glaucoma patients of African and European descent. Cataract surgery was the strongest predictor of variability; excluding it eliminated racial differences, suggesting RNFLT reliability across races.

Nishida Takashi, Moghimi Sasan, Walker Evan, Gunasegaran Gopikasree, Wu Jo-Hsuan, Kamalipour Alireza et al.

This study found that increasing foveal avascular zone (FAZ) area in glaucoma patients is weakly associated with faster retinal nerve fiber layer thinning and visual field loss, suggesting a potential progression marker.

Bowd Christopher, Belghith Akram, Rezapour Jasmin, Jonas Jost B, Hyman Leslie, Weinreb Robert N et al.

Wide-field OCT, combining optic nerve and macula scans, better detected retinal nerve fiber layer thinning rates in progressing glaucoma, improving monitoring for patients with or without high myopia.

Tansuebchueasai Natchada, Nishida Takashi, Moghimi Sasan, Wu Jo-Hsuan, Mahmoudinezhad Golnoush, Gunasegaran Gopikasree et al.

Rapid initial optic nerve head capillary density loss (OCTA) was linked to faster visual field progression and doubled progression risk, suggesting OCTA aids early glaucoma risk assessment.

Kamalipour Alireza, Moghimi Sasan, Khosravi Pooya, Tansuebchueasai Natchada, Vasile Cristiana, Adelpour Mohsen et al.

This study found papillomacular and papillofoveal retinal nerve fiber layer defects are common in glaucoma and strongly predict central visual field loss detected by 10-2 testing.