Hyman Leslie

VanderBeek Brian L, Chen Yineng, Tomaiuolo Maurizio, Deaner Jordan D, Syed Zeba A, Acharya Binod et al.

This study found endophthalmitis rates after intraocular procedures decreased over 20 years. Concurrently, prompt vitrectomy for treatment became less common, suggesting evolving management strategies.

Bowd Christopher, Belghith Akram, Rezapour Jasmin, Jonas Jost B, Hyman Leslie, Weinreb Robert N et al.

Wide-field OCT, combining optic nerve and macula scans, better detected retinal nerve fiber layer thinning rates in progressing glaucoma, improving monitoring for patients with or without high myopia.

Rezapour Jasmin, Walker Evan, Belghith Akram, Bowd Christopher, Fazio Massimo A, Jiravarnsirikul Anuwat et al.

This study found OCT parameters effectively detect glaucoma, but accuracy varies with myopia. Macula parameters (GCIPL) showed high diagnostic promise for glaucoma in highly myopic eyes.

Bowd Christopher, Belghith Akram, Rezapour Jasmin, Christopher Mark, Jonas Jost B, Hyman Leslie et al.

A deep learning model combining OCT scans and texture data better diagnosed glaucoma, especially in highly myopic eyes, offering improved diagnostic accuracy.

Rezapour Jasmin, Bowd Christopher, Dohleman Jade, Belghith Akram, Proudfoot James A, Christopher Mark et al.

This study found macular GCIPL and GCC thickness correlate with glaucoma severity, not axial length, making them useful for monitoring glaucoma in highly myopic eyes.

Bowd Christopher, Belghith Akram, Rezapour Jasmin, Christopher Mark, Hyman Leslie, Jonas Jost B et al.

A novel OCT texture analysis (SALSA-Texture) improved glaucoma detection in high myopes compared to traditional thickness maps, offering a promising tool where standard segmentation is challenging.

Marsh-Tootle Wendy L, Harb Elise, Hou Wei, Zhang Qinghua, Anderson Heather A, Weise Katherine et al.

This study found myopic young adults have more optic nerve tilt and crescents, with ethnicity influencing these characteristics. This clarifies myopia's impact on ONH structure, aiding future pathology research.

Polla Daniel, Astafurov Konstantin, Hawy Eman, Hyman Leslie, Hou Wei, Danias John

This study found primary open-angle glaucoma (POAG) was associated with fewer natural teeth and altered oral bacteria, suggesting a potential link between oral health and glaucoma pathology.

Pasquale Louis R, Hyman Leslie, Wiggs Janey L, Rosner Bernard A, Joshipura Kaumudi, McEvoy Mark et al.

This study found recent tooth loss, especially with periodontal disease, was associated with increased primary open-angle glaucoma risk in men. This suggests a potential oral-systemic link to glaucoma, needing further confirmation.

Heijl Anders, Leske M Cristina, Hyman Leslie, Yang Zhongming, Bengtsson Boel

This study found that a fixed glaucoma treatment's IOP reduction strongly depends on baseline pressure, with minimal effect below 15 mmHg. This highlights the importance of reporting baseline IOP in treatment outcomes.

Heijl Anders, Bengtsson Boel, Hyman Leslie, Leske M Cristina

This EMGT study found untreated glaucoma progression rates vary significantly by type, with pseudoexfoliation glaucoma progressing fastest and normal-tension glaucoma slowest, informing prognosis and treatment urgency.

Heijl Anders, Bengtsson Boel, Chauhan Balwantray C, Lieberman Marc F, Cunliffe Ian, Hyman Leslie et al.

This study compared glaucoma trial visual field progression criteria, finding EMGT criteria detected progression earliest and most frequently, but with slightly lower specificity, impacting early intervention decisions.

Leske M Cristina, Heijl Anders, Hyman Leslie, Bengtsson Boel, Dong LiMing, Yang Zhongming

This study identified new glaucoma progression predictors—lower perfusion pressure, cardiovascular disease, and thinner corneas—beyond IOP and established risk factors, highlighting vascular health's role in disease management.

Bengtsson Boel, Leske M Cristina, Hyman Leslie, Heijl Anders

This study found that while higher mean IOP is a strong risk factor for glaucoma progression, IOP fluctuation itself was not an independent predictor of progression in early manifest glaucoma.

Leske M Cristina, Heijl Anders, Hyman Leslie, Bengtsson Bo, Komaroff Eugene

The EMGT found early glaucoma treatment (IOP lowering) halved progression risk, highlighting its value, while age and disease severity also predicted worsening.**