An automated optical coherence tomography to finite element analysis pipeline reveals key morphological determinants of optic nerve head biomechanics in glaucoma.
Li Qi, Zhan Bohan, Liu Tingting, Han Yingxiang, Xin Sanfeng, Chen Zengsheng et al.
Automated OCT-based models show lamina cribrosa depth strongly predicts strain. Glaucomatous eyes exhibit lower strain, suggesting remodeling. This scalable tool offers patient-specific biomechanical insights for improved glaucoma risk stratification and monitoring.