Hardin Christy

Jeoung Jin Wook, Yang Hongli, Gardiner Stuart, Wang Ya Xing, Hong Seungwoo, Fortune Brad et al.

This study found highly myopic eyes have greater optic nerve head obliqueness and ASCO/BMO offset, leading to a smaller neural canal area, which impacts glaucoma assessment.

Wang Ya Xing, Yang Hongli, Luo Haomin, Hong Seung Woo, Gardiner Stuart K, Jeoung Jin Wook et al.

OCT showed peripapillary scleral bowing increases with age and links to thinner choroids in healthy eyes. This provides a baseline for glaucoma and myopia research.

Yang Hongli, Luo Haomin, Hardin Christy, Wang Yaxing, Jeoung Jin Wook, Albert Cindy et al.

This study found that combining topographically aligned OCT rim width and nerve fiber layer measurements accurately detects glaucoma, offering high diagnostic precision for identifying structural damage.

Hong Seungwoo, Yang Hongli, Gardiner Stuart K, Luo Haomin, Hardin Christy, Sharpe Glen P et al.

This study found the optic nerve's narrowest point (NCMCA) is smaller than its openings and correlates best with RNFLT, whose distribution is influenced by neural canal direction, offering insights into glaucoma risk.

Yang Hongli, Luo Haomin, Gardiner Stuart K, Hardin Christy, Sharpe Glen P, Caprioli Joseph et al.

This study found peripapillary choroidal thickness (PCT) in healthy eyes is thinnest inferior-temporally and decreases with age, axial length, and European descent, with age being the strongest factor, especially in thinner sectors.

Luo Haomin, Yang Hongli, Gardiner Stuart K, Hardin Christy, Sharpe Glen P, Caprioli Joseph et al.

This study found central lamina cribrosa depth in healthy eyes varies with age, sex, and eye size. African descent eyes had deeper central lamina, but the clinical importance of these small differences is still unknown.

Yang Hongli, Reynaud Juan, Lockwood Howard, Williams Galen, Hardin Christy, Reyes Luke et al.

This monkey study found glaucoma causes optic nerve head connective tissue deformation and remodeling, driven by cellular mechanobiology, leading to nerve damage. This highlights connective tissue as a therapeutic target.

Fortune Brad, Reynaud Juan, Hardin Christy, Wang Lin, Sigal Ian A, Burgoyne Claude F

Experimental glaucoma in monkeys caused significantly more optic nerve head neural rim thinning than peripapillary nerve fiber layer thinning, suggesting axon compression within the optic nerve head.

Fortune Brad, Hardin Christy, Reynaud Juan, Cull Grant, Yang Hongli, Wang Lin et al.

This study found peripapillary RNFLT correlates best with actual axon loss in experimental glaucoma, suggesting it's a more reliable SDOCT measure than optic nerve head rim parameters for monitoring disease.

Yang Hongli, Qi Jingjing, Hardin Christy, Gardiner Stuart K, Strouthidis Nicholas G, Fortune Brad et al.

EDI significantly improved visibility of the optic nerve's posterior lamina cribrosa in nonhuman primates, especially in glaucoma, potentially aiding earlier disease detection and monitoring.