22 articles in GJC
Intraocular Pressure after Phacoemulsification with Retained Lens Fragments in the IRIS® Registry (Intelligent Research in Sight).
Rothman Adam L, Persad Lomas S, Paranjpe Vikram R, Chang Ta Chen, Lum Flora, Vanner Elizabeth A et al.
This study found that retained lens fragments after cataract surgery cause higher initial IOP elevation and spikes, especially in males, those with higher baseline IOP, or glaucoma, necessitating vigilant monitoring.
Outcomes of Patients with Proliferative Diabetic Retinopathy Treated with Anti-VEGF Therapy and/or Panretinal Photocoagulation in the United States Who Were Lost to Follow-up.
Khurana Rahul N, Wang Jay C, Zhang Sen, Li Charles, Lum Flora
PDR patients lost to follow-up experience significant vision loss and complications upon return, especially without PRP monotherapy. Adherence is crucial to prevent irreversible vision loss.
Vision Loss and Blindness in the United States: An Age-Adjusted Comparison by Sex and Associated Disease Category.
Bugg Victoria A, Eppich Kaleb, Blakley Macey S, Lum Flora, Greene Tom, Hartnett M Elizabeth
This study found US women have more vision loss/blindness than men, especially from cataracts and AMD. This highlights sex-specific disease burdens for clinical focus.
Special Commentary: Reporting Clinical Endpoints in Studies of Minimally Invasive Glaucoma Surgery.
Gedde Steven J, Vinod Kateki, Bowden Eileen C, Kolomeyer Natasha N, Chopra Vikas, Challa Pratap et al.
This paper standardized MIGS clinical endpoints and defined Minimal Clinically Important Differences (MCID) for success, improving study comparison and ensuring patient-meaningful outcomes in glaucoma care.
Intraocular Pressure Spike Following Stand-Alone Phacoemulsification in the IRIS® Registry (Intelligent Research in Sight).
Lidder Alcina K, Vanner Elizabeth A, Chang Ta Chen, Lum Flora, Rothman Adam L
This study identified risk factors like higher baseline IOP, male sex, and glaucoma for post-cataract surgery IOP spikes, helping surgeons stratify and mitigate patient risk.
Prevalence and Risk Factors of Blindness Among Primary Angle Closure Glaucoma Patients in the United States: An IRIS Registry Analysis.
Shah Sona N, Zhou Sarah, Sanvicente Carina, Burkemper Bruce, Apolo Galo, Li Charles et al.
This study found 1 in 9 newly diagnosed US PACG patients are blind. Black/Hispanic race and public insurance increase blindness risk, highlighting disparities and need for earlier detection.
Tube Versus Trabeculectomy IRIS Registry Study: 1-Year Secondary Treatment Outcomes.
Sun Catherine Q, McSoley Matthew J, Lum Flora, Chang Ta C, Gedde Steven J, Vanner Elizabeth A
Real-world data showed similar 1-year IOP reduction for tube shunts and trabeculectomy, but trabeculectomy used fewer medications, informing surgical choice for glaucoma.
Vitreoretinopathy-Associated Pediatric Retinal Detachment Treatment Outcomes: IRIS® Registry (Intelligent Research in Sight) Analysis.
Belin Peter J, Naravane Ameay V, Lu Siying, Li Charles, Lum Flora, Quiram Polly A
This study of pediatric vitreoretinopathy-associated RDs found high reoperation rates and frequent fellow eye involvement, highlighting the complex, often bilateral nature of these rare detachments.
Intraocular Pressure Changes Following Stand-Alone Phacoemulsification: An IRIS Ɍ Registry Analysis.
Rothman Adam L, Chang Ta Chen, Lum Flora, Vanner Elizabeth A
Stand-alone cataract surgery significantly lowered intraocular pressure in both glaucoma and non-glaucoma patients through 90 days post-op, offering a beneficial IOP reduction.
Risk Factors for Repeat Keratoplasty After Endothelial Keratoplasty-An IRIS Registry Analysis.
Son Hyeck-Soo, Lum Flora, Li Charles, Schein Oliver, Pramanik Sudeep, Srikumaran Divya
This study identified risk factors for repeat corneal transplants after EK. Key findings include prior graft failure, glaucoma, and social determinants like Black race and government insurance, informing patient counseling and care.
An IRIS Registry-Based Assessment of Primary Open-Angle Glaucoma Practice Patterns in Academic Versus Nonacademic Settings.
Skuta Gregory L, Ding Kai, Lum Flora, Coleman Anne L
IRIS Registry data showed academic glaucoma practices treat more severe cases and Black patients, use more diagnostics, and perform different surgeries than nonacademic settings, highlighting educational opportunities.
Etiology, Treatment Patterns, and Outcomes for Choroidal Neovascularization in the Pediatric Population: An Intelligent Research in Sight (IRIS®) Registry Study.
Finn Avni P, Fujino Danielle, Lum Flora, Rao Prethy
A large study of pediatric CNV found common causes are idiopathic, inflammatory, or myopia. Treated eyes, typically older with worse initial vision, showed significant and sustained visual improvement.
Reply to Comment on: The Tube Versus Trabeculectomy IRIS Ⓡ Registry Study: Cohort Selection and Follow-up and Comparisons to the Randomized Controlled Trial.
Vanner Elizabeth A, Sun Catherine Q, McSoley Matthew J, Persad Patrice J, Feuer William J, Lum Flora et al.
Tube Versus Trabeculectomy IRIS Ⓡ Registry 1-Year Composite Outcome Analysis with Comparisons to the Randomized Controlled Trial.
Vanner Elizabeth A, Sun Catherine Q, McSoley Matthew J, Persad Patrice J, Feuer William J, Lum Flora et al.
This study compared real-world (IRIS Registry) tube vs. trabeculectomy outcomes. It found real-world tube shunt failure rates were higher than in the RCT, suggesting real-world practice differences impact outcomes.
Demographic and Clinical Characteristics Associated with Minimally Invasive Glaucoma Surgery Use: An Intelligent Research in Sight (IRIS®) Registry Retrospective Cohort Analysis.
Olivier Mildred M G, Smith Oluwatosin U, Croteau-Chonka Clarisse C, VanderBeek Brian L, Maguire Maureen G, Lum Flora et al.
This study found MIGS use during cataract surgery varied by age, race, insurance, region, and glaucoma severity, suggesting diverse patient selection patterns.
The Tube Versus Trabeculectomy IRIS® Registry Study: Cohort Selection and Follow-up and Comparisons to the Randomized Controlled Trial.
Vanner Elizabeth A, Sun Catherine Q, McSoley Matthew J, Persad Patrice J, Feuer William J, Lum Flora et al.
This study found real-world registry data for glaucoma surgeries (tube vs. trabeculectomy) had significant baseline differences and poorer follow-up compared to a controlled trial, limiting direct comparisons and generalizability.
Risk of Glaucoma Surgery After Corneal Transplant Surgery in Medicare Patients.
Zheng Chengjie, Yu Fei, Tseng Victoria L, Lum Flora, Coleman Anne L
This study found no difference in glaucoma surgery rates among various corneal transplants, but patients with pre-existing glaucoma, especially after PK, had significantly higher risk, requiring careful long-term management.
The Real-World Effect of Intravitreous Anti-Vascular Endothelial Growth Factor Drugs on Intraocular Pressure: An Analysis Using the IRIS Registry.
Atchison Elizabeth A, Wood Kevin M, Mattox Cynthia G, Barry Catherine N, Lum Flora, MacCumber Mathew W
Real-world data show anti-VEGF injections generally cause a small IOP decrease, but 2.6% of patients experienced a significant rise (except with aflibercept), highlighting the need for continued IOP monitoring.
Risk of fractures following cataract surgery in Medicare beneficiaries.
Tseng Victoria L, Yu Fei, Lum Flora, Coleman Anne L
This study found cataract surgery significantly reduced hip fracture risk in Medicare beneficiaries with cataracts, suggesting improved vision may prevent falls and fractures.
The value of regular examinations to detect glaucoma and other chronic conditions among older Americans.
Javitt Jonathan, Lee Paul, Lum Flora
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